Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHS33_RS17015 Genome accession   NZ_CP107819
Coordinates   3913482..3914141 (+) Length   219 a.a.
NCBI ID   WP_330331257.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00536     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3908482..3919141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHS33_RS16995 (OHS33_16990) - 3908874..3910076 (+) 1203 WP_330331253.1 acyltransferase -
  OHS33_RS17000 (OHS33_16995) - 3910087..3911409 (+) 1323 WP_330331254.1 sensor histidine kinase -
  OHS33_RS17005 (OHS33_17000) vraR 3911406..3912077 (+) 672 WP_330331255.1 response regulator transcription factor Regulator
  OHS33_RS17010 (OHS33_17005) - 3912166..3913485 (+) 1320 WP_330331256.1 histidine kinase -
  OHS33_RS17015 (OHS33_17010) vraR 3913482..3914141 (+) 660 WP_330331257.1 response regulator transcription factor Regulator
  OHS33_RS17020 (OHS33_17015) - 3914169..3915383 (+) 1215 WP_330331258.1 cytochrome P450 -
  OHS33_RS17025 (OHS33_17020) - 3915432..3916202 (+) 771 WP_330331259.1 MBL fold metallo-hydrolase -
  OHS33_RS17030 (OHS33_17025) - 3916262..3917005 (-) 744 WP_330331260.1 response regulator transcription factor -
  OHS33_RS17035 (OHS33_17030) - 3917002..3918252 (-) 1251 WP_330331261.1 histidine kinase -
  OHS33_RS17040 (OHS33_17035) - 3918388..3918807 (+) 420 WP_330331262.1 DUF4190 domain-containing protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23745.56 Da        Isoelectric Point: 4.5783

>NTDB_id=646589 OHS33_RS17015 WP_330331257.1 3913482..3914141(+) (vraR) [Streptomyces sp. NBC_00536]
MSIRVLIVDDQMMVREGFSVLLGAMPGIEVVGEAVDGREAVERVAELRPDVVLMDIRMPVMNGLEATRQIVAADADAKVL
VLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVSSGEALLAPSVTKRLIVEFAKLAQTPRVADPGMVEELTERE
TEVLILIAQGLSNAEIADRLVVAESTIKTHVSRILVKLGLRDRTQAAVYAYETRLVSPS

Nucleotide


Download         Length: 660 bp        

>NTDB_id=646589 OHS33_RS17015 WP_330331257.1 3913482..3914141(+) (vraR) [Streptomyces sp. NBC_00536]
ATGAGCATCCGGGTGCTGATCGTGGACGATCAGATGATGGTTCGGGAGGGCTTCTCCGTCCTGCTGGGCGCGATGCCGGG
CATCGAGGTGGTCGGGGAGGCGGTCGACGGCCGTGAGGCCGTGGAGCGGGTGGCCGAGCTGCGGCCGGACGTGGTGCTGA
TGGACATCCGGATGCCGGTGATGAACGGCCTGGAGGCGACGCGGCAGATCGTGGCGGCGGACGCGGACGCGAAGGTGCTG
GTGCTGACGACCTTCGACCTCGATGAATACGTGTACCAGGCGCTGCGGGCCGGAGCCTCGGGGTTCCTGCTCAAGGACGC
GTCCGCCCGGCAACTGGCCGACGGGGTGCGGGTGGTGTCGTCCGGCGAGGCGCTGCTGGCGCCGTCGGTGACCAAGCGGC
TGATCGTGGAGTTCGCGAAGCTCGCGCAGACGCCCCGGGTGGCGGATCCGGGAATGGTGGAGGAGCTGACGGAGCGGGAG
ACGGAGGTGCTGATCCTGATCGCCCAGGGGCTGTCCAATGCGGAGATAGCCGACCGCCTGGTGGTCGCGGAGTCCACGAT
CAAGACCCATGTCAGCCGGATCCTGGTCAAGTTGGGTCTGCGGGACCGCACCCAGGCCGCTGTCTACGCGTATGAGACCC
GCCTGGTCTCCCCCTCGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.296

98.63

0.457
  degU Bacillus subtilis subsp. subtilis str. 168

41.964

100

0.429