Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG956_RS28520 Genome accession   NZ_CP107796
Coordinates   6489261..6489902 (+) Length   213 a.a.
NCBI ID   WP_330340871.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00557     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6484261..6494902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG956_RS28500 (OG956_28495) - 6484991..6485758 (-) 768 WP_330340868.1 transglycosylase SLT domain-containing protein -
  OG956_RS28505 (OG956_28500) - 6486060..6487202 (-) 1143 WP_330340869.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG956_RS28510 (OG956_28505) - 6487199..6487894 (-) 696 WP_330342971.1 SDR family oxidoreductase -
  OG956_RS28515 (OG956_28510) - 6488123..6489268 (+) 1146 WP_330340870.1 GAF domain-containing sensor histidine kinase -
  OG956_RS28520 (OG956_28515) vraR 6489261..6489902 (+) 642 WP_330340871.1 response regulator transcription factor Regulator
  OG956_RS28525 (OG956_28520) - 6490074..6490319 (+) 246 WP_330340872.1 chaplin -
  OG956_RS28530 (OG956_28525) - 6490816..6491604 (-) 789 WP_330340873.1 hypothetical protein -
  OG956_RS28535 (OG956_28530) - 6491755..6492546 (+) 792 WP_330340874.1 ABC transporter ATP-binding protein -
  OG956_RS28540 (OG956_28535) - 6492609..6493040 (+) 432 WP_330340875.1 NfeD family protein -
  OG956_RS28545 (OG956_28540) - 6493151..6494119 (+) 969 WP_330340876.1 SPFH domain-containing protein -
  OG956_RS28550 (OG956_28545) - 6494230..6494736 (-) 507 WP_330340877.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23018.28 Da        Isoelectric Point: 5.3665

>NTDB_id=646373 OG956_RS28520 WP_330340871.1 6489261..6489902(+) (vraR) [Streptomyces sp. NBC_00557]
MADAIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARAEELRPDVVLMDVKMPGMDGIEALRRLRELDHPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHVLLQPEVAGALLSQEEANSGQGRAGSLTEREREVL
GLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=646373 OG956_RS28520 WP_330340871.1 6489261..6489902(+) (vraR) [Streptomyces sp. NBC_00557]
GTGGCTGACGCGATCAGGGTGCTGCTCGTCGACGACCACCAGGTCGTCCGGCGGGGCCTGCGCACCTTTCTGGAGGTGCA
GGACGACATAGAGGTCGTCGGCGAGGCCGCCGACGGTGCCGAGGGAGTCGCCCGCGCCGAGGAACTGCGGCCGGACGTCG
TCCTGATGGACGTCAAGATGCCCGGCATGGACGGCATCGAGGCCCTGCGCCGACTGCGCGAGCTCGACCACCCCGCGCGC
GTGCTCATCGTCACCAGCTTCACCGAGCAGCGCACCGTCGTACCGGCCCTGCGCGCGGGCGCCGCCGGGTACGTCTACAA
GGACGTGGACCCCGACGCCCTCGCCGGGGCCATCCGCTCCGTGCACGCCGGCCACGTCCTGCTGCAGCCCGAGGTCGCCG
GCGCCCTGCTCTCCCAGGAGGAGGCCAACTCGGGCCAGGGCAGAGCCGGTTCGCTCACCGAGCGGGAGCGCGAGGTGCTC
GGCCTGATCGCGGACGGCCGCTCCAACCGGGAGATCGCCCGCGCCCTCGTGCTCTCCGAGAAGACCGTCAAGACGCACGT
CTCCAACATCCTCATGAAACTCGACCTCGCCGACCGCACGCAGGCCGCGTTGTGGGCCGTGCGCCACGGCGTGACCGGCT
GA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.698

99.531

0.465
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.399