Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA33_RS18205 Genome accession   NZ_CP107791
Coordinates   4078639..4079316 (-) Length   225 a.a.
NCBI ID   WP_330245165.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00562     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4073639..4084316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA33_RS18180 (OHA33_18215) panC 4073717..4074727 (-) 1011 WP_330245160.1 pantoate--beta-alanine ligase -
  OHA33_RS18185 (OHA33_18220) - 4074724..4075683 (-) 960 WP_330245161.1 DUF2520 domain-containing protein -
  OHA33_RS18190 (OHA33_18225) - 4075866..4077101 (+) 1236 WP_330245162.1 beta-eliminating lyase-related protein -
  OHA33_RS18195 (OHA33_18230) - 4077138..4077398 (-) 261 WP_330245163.1 hypothetical protein -
  OHA33_RS18200 (OHA33_18235) - 4077503..4078615 (+) 1113 WP_330245164.1 DUF5937 family protein -
  OHA33_RS18205 (OHA33_18240) vraR 4078639..4079316 (-) 678 WP_330245165.1 response regulator transcription factor Regulator
  OHA33_RS18210 (OHA33_18245) - 4079359..4080558 (-) 1200 WP_330245166.1 sensor histidine kinase -
  OHA33_RS18215 (OHA33_18250) - 4080655..4081686 (+) 1032 WP_330245167.1 SAM-dependent methyltransferase -
  OHA33_RS18220 (OHA33_18255) - 4081812..4082954 (+) 1143 WP_330245168.1 NADH-quinone oxidoreductase subunit D -
  OHA33_RS18225 (OHA33_18260) - 4083009..4084022 (-) 1014 WP_330245169.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24204.14 Da        Isoelectric Point: 6.2654

>NTDB_id=646269 OHA33_RS18205 WP_330245165.1 4078639..4079316(-) (vraR) [Streptomyces sp. NBC_00562]
MAIRVMLVDDQVLLRTGFRMVLAAQPDMEVVAEAGDGAEAIENLRSIAVDVVLMDVRMPRLDGVEATRRICARPDAPKVL
ILTTFDLDEYAFSGLKAGASGFMLKDVPPAELLGAIRSVHSGDAVVAPSTTRRLLDRFSSMLPSSTDEPKHKDIGKLTER
EREVMLLVAQGMSNGEIAARLVLSEATVKTHVGRILTKLNLRDRVQVVVLAYETGLVRAGGGGAG

Nucleotide


Download         Length: 678 bp        

>NTDB_id=646269 OHA33_RS18205 WP_330245165.1 4078639..4079316(-) (vraR) [Streptomyces sp. NBC_00562]
ATGGCGATCCGCGTGATGCTCGTCGACGACCAGGTGCTGCTGCGCACCGGCTTCCGGATGGTGCTCGCGGCGCAGCCGGA
CATGGAGGTCGTCGCCGAGGCCGGCGACGGCGCGGAGGCGATCGAGAACCTTCGCTCCATCGCCGTCGACGTGGTGCTGA
TGGACGTGCGCATGCCGAGGCTGGACGGTGTCGAGGCGACCCGGCGCATCTGCGCCCGGCCCGATGCGCCCAAGGTGCTC
ATCCTGACCACGTTCGACCTGGACGAATACGCCTTCTCCGGTCTGAAGGCCGGGGCCAGCGGTTTCATGCTCAAGGACGT
GCCGCCGGCCGAACTGCTCGGCGCGATCCGTTCGGTGCACAGCGGCGACGCGGTCGTCGCCCCGTCCACCACCCGGCGGC
TGCTCGACCGCTTCTCGTCCATGCTGCCGAGCAGCACCGACGAACCCAAGCACAAGGACATCGGCAAGCTCACCGAACGC
GAACGCGAAGTGATGCTGCTGGTCGCGCAGGGCATGTCGAACGGCGAGATCGCGGCGCGGCTGGTGCTCTCCGAGGCGAC
GGTGAAGACACACGTCGGCCGCATCCTCACCAAGCTGAACCTGCGCGACCGGGTGCAGGTCGTCGTGCTCGCGTACGAGA
CGGGGCTGGTGCGGGCCGGTGGAGGCGGGGCGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-211)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.557

98.222

0.369
  degU Bacillus subtilis subsp. subtilis str. 168

37.22

99.111

0.369