Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA33_RS10035 Genome accession   NZ_CP107791
Coordinates   2252592..2253236 (-) Length   214 a.a.
NCBI ID   WP_267005898.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00562     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2247592..2258236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA33_RS10005 (OHA33_10025) - 2248109..2248615 (+) 507 WP_030920231.1 HNH endonuclease -
  OHA33_RS10010 (OHA33_10030) - 2248783..2249715 (-) 933 WP_313936606.1 SPFH domain-containing protein -
  OHA33_RS10015 (OHA33_10035) - 2249842..2250270 (-) 429 WP_267005901.1 NfeD family protein -
  OHA33_RS10020 (OHA33_10040) - 2250325..2251122 (-) 798 WP_267005900.1 ABC transporter ATP-binding protein -
  OHA33_RS10025 (OHA33_10045) - 2251246..2252028 (+) 783 WP_330244084.1 hypothetical protein -
  OHA33_RS10030 (OHA33_10050) - 2252196..2252444 (-) 249 WP_030974440.1 chaplin family protein -
  OHA33_RS10035 (OHA33_10055) vraR 2252592..2253236 (-) 645 WP_267005898.1 response regulator transcription factor Regulator
  OHA33_RS10040 (OHA33_10060) - 2253229..2254374 (-) 1146 WP_330244085.1 GAF domain-containing sensor histidine kinase -
  OHA33_RS10045 (OHA33_10065) - 2254567..2255310 (+) 744 WP_330244086.1 SDR family NAD(P)-dependent oxidoreductase -
  OHA33_RS10050 (OHA33_10070) - 2255289..2256410 (+) 1122 WP_330244087.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHA33_RS10055 (OHA33_10075) - 2256697..2257446 (+) 750 WP_330244088.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23051.37 Da        Isoelectric Point: 5.1683

>NTDB_id=646250 OHA33_RS10035 WP_267005898.1 2252592..2253236(-) (vraR) [Streptomyces sp. NBC_00562]
MADKIIRVLLVDDHQVVRRGLRTFLEIQDDIEVVGEAADGAEGVARSEELRPDVVLMDIKMPGTDGIEALRKLRELENPA
KVLIVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIRSVYAGHVLLQPEVAGALLAQEDAGGGTGRGSTLTEREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLSDRTQAALWAVRHGVAG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=646250 OHA33_RS10035 WP_267005898.1 2252592..2253236(-) (vraR) [Streptomyces sp. NBC_00562]
GTGGCTGACAAGATCATCAGGGTGCTGCTGGTCGACGACCACCAGGTGGTCCGCCGCGGTCTGCGTACGTTCCTGGAGAT
CCAGGACGACATAGAGGTCGTCGGCGAGGCGGCCGACGGCGCGGAGGGCGTGGCCAGGAGCGAGGAGCTGCGCCCCGACG
TGGTCCTGATGGACATCAAGATGCCGGGCACGGACGGCATCGAGGCGCTCCGCAAGCTCCGGGAGCTGGAGAACCCGGCC
AAGGTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTCCCTGCCCTGCGCGCGGGCGCCTCCGGTTACGTATA
CAAGGACGTCGACCCGGACGCACTCGCCGGGGCCATCCGCTCGGTGTACGCGGGCCATGTCCTGCTCCAGCCGGAGGTCG
CCGGAGCCCTGCTCGCCCAGGAGGACGCCGGCGGCGGTACGGGCCGGGGGAGCACTCTCACCGAACGGGAGCGGGAAGTA
CTGGGCCTGATCGCCGACGGCCGTTCCAACCGTGAGATCGCCAGGGCGCTGGTCCTCTCCGAGAAGACCGTGAAGACGCA
CGTCTCGAACATTCTGATGAAGCTGGATCTGTCGGACCGCACCCAGGCCGCCCTCTGGGCCGTCCGACATGGGGTAGCAG
GCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-207)

Response regulator receiver domain (Response_reg)

(8-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.928

96.729

0.435
  degU Bacillus subtilis subsp. subtilis str. 168

39.367

100

0.407