Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHA33_RS07140 Genome accession   NZ_CP107791
Coordinates   1607524..1608174 (+) Length   216 a.a.
NCBI ID   WP_326602344.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00562     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1602524..1613174
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHA33_RS07115 (OHA33_07130) mug 1603365..1603922 (+) 558 WP_330243732.1 G/U mismatch-specific DNA glycosylase -
  OHA33_RS07120 (OHA33_07135) - 1603998..1604435 (-) 438 WP_330243733.1 hypothetical protein -
  OHA33_RS07125 (OHA33_07140) - 1604560..1605303 (-) 744 WP_330248806.1 ABC transporter permease -
  OHA33_RS07130 (OHA33_07145) - 1605300..1606238 (-) 939 WP_330243734.1 ATP-binding cassette domain-containing protein -
  OHA33_RS07135 (OHA33_07150) - 1606347..1607519 (+) 1173 WP_330243735.1 histidine kinase -
  OHA33_RS07140 (OHA33_07155) vraR 1607524..1608174 (+) 651 WP_326602344.1 response regulator transcription factor Regulator
  OHA33_RS07145 (OHA33_07160) - 1608274..1609431 (+) 1158 WP_330243736.1 ROK family transcriptional regulator -
  OHA33_RS07150 (OHA33_07165) - 1609481..1610248 (-) 768 WP_330243737.1 GntR family transcriptional regulator -
  OHA33_RS07155 (OHA33_07170) - 1610514..1611398 (-) 885 WP_330243738.1 RNA polymerase sigma-70 factor -
  OHA33_RS07160 (OHA33_07175) - 1611589..1612419 (+) 831 WP_330243739.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23049.94 Da        Isoelectric Point: 6.2675

>NTDB_id=646246 OHA33_RS07140 WP_326602344.1 1607524..1608174(+) (vraR) [Streptomyces sp. NBC_00562]
MPVTVLLVDDEPLVRAGLRAVLEAQPDIEVVGEAADGAAVIPLVHKLRPDVVAMDVRMPLMDGIEATRVVLRTVPDPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPAAVRQLAAEYGTSKAKAVMKRASLTEREAAV
LRLMARGLSNAEIAAKLVVGVETVKTHVSAVLAKLGARDRTQAVIAAYESGFVAPS

Nucleotide


Download         Length: 651 bp        

>NTDB_id=646246 OHA33_RS07140 WP_326602344.1 1607524..1608174(+) (vraR) [Streptomyces sp. NBC_00562]
ATGCCGGTTACCGTTCTTCTGGTCGACGACGAACCTCTCGTACGCGCGGGGCTGCGCGCGGTCCTTGAGGCTCAGCCCGA
TATCGAGGTGGTGGGCGAGGCGGCGGACGGCGCAGCAGTGATCCCGCTGGTGCACAAGTTGCGCCCCGATGTGGTGGCGA
TGGATGTGCGGATGCCCTTGATGGACGGCATCGAGGCGACCCGGGTGGTGCTGCGCACGGTGCCTGATCCGCCGAAGATC
CTGGTGGTGACGACATTCGAGAACGACGAGTACGTGTACGAGGCGCTGCGCGCCGGGGCGGACGGCTTTCTGCTCAAGCG
TGCCCGGCCCGCGGAGATCGTGCATGCGGTGCGCCTGGTCGCCGAGGGGGAGTCTCTGCTGTTCCCGGCCGCGGTCCGGC
AGCTCGCCGCCGAGTACGGGACGAGCAAGGCGAAGGCGGTCATGAAGCGGGCCTCGCTCACCGAGCGCGAGGCTGCGGTG
CTCCGGCTGATGGCCCGGGGACTCTCGAATGCGGAGATCGCCGCCAAGCTCGTGGTCGGCGTCGAGACGGTGAAGACCCA
TGTCAGCGCAGTGCTGGCAAAGTTGGGGGCCAGGGATCGGACCCAGGCGGTGATCGCCGCGTACGAGTCCGGCTTCGTGG
CTCCGAGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(152-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.396

100

0.426
  degU Bacillus subtilis subsp. subtilis str. 168

36.607

100

0.38