Detailed information NTG0646129

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: L1A13_RS04730
• Genome accession: NZ_CP090889
• Coordinates: 917260..918213 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain CH2439
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 912260..923213

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A13_RS04705 (L1A13_04705)	rpmG	913003..913152 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
L1A13_RS04710 (L1A13_04710)	secG	913192..913425 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
L1A13_RS04715 (L1A13_04715)	rnr	913527..915881 (+)	2355	WP_000654920.1	ribonuclease R	-
L1A13_RS04720 (L1A13_04720)	smpB	915844..916311 (+)	468	WP_001051753.1	SsrA-binding protein SmpB	-
L1A13_RS04725 (L1A13_04725)	tehB	916327..917187 (+)	861	WP_000413769.1	SAM-dependent methyltransferase TehB	-
L1A13_RS04730 (L1A13_04730)	coiA	917260..918213 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
L1A13_RS04735 (L1A13_04735)	pepF	918232..920034 (+)	1803	WP_000244134.1	oligoendopeptidase F	Regulator
L1A13_RS04740 (L1A13_04740)	-	920036..920749 (+)	714	WP_000230399.1	O-methyltransferase	-
L1A13_RS04745 (L1A13_04745)	prsA	920816..921757 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
L1A13_RS04750 (L1A13_04750)	-	921876..922217 (-)	342	Protein_932	IS3 family transposase	-
L1A13_RS04755 (L1A13_04755)	-	922630..922725 (+)	96	Protein_933	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=646129 L1A13_RS04730 WP_000495909.1 917260..918213(+) (coiA) [Streptococcus pneumoniae strain CH2439]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=646129 L1A13_RS04730 WP_000495909.1 917260..918213(+) (coiA) [Streptococcus pneumoniae strain CH2439]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435