Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   L1A13_RS00260 Genome accession   NZ_CP090889
Coordinates   40815..41768 (+) Length   317 a.a.
NCBI ID   WP_000345099.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain CH2439     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 35815..46768
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A13_RS00215 (L1A13_00215) - 35872..36237 (+) 366 WP_000286415.1 DUF1033 family protein -
  L1A13_RS00220 (L1A13_00220) comGA/cglA/cilD 36313..37254 (+) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  L1A13_RS00225 (L1A13_00225) comGB/cglB 37202..38218 (+) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  L1A13_RS00230 (L1A13_00230) comGC/cglC 38220..38546 (+) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  L1A13_RS00235 (L1A13_00235) comGD/cglD 38539..38943 (+) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  L1A13_RS00240 (L1A13_00240) comGE/cglE 38906..39208 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  L1A13_RS00245 (L1A13_00245) comGF/cglF 39171..39632 (+) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  L1A13_RS00250 (L1A13_00250) comGG/cglG 39610..40023 (+) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  L1A13_RS00255 (L1A13_00255) - 40160..40754 (+) 595 Protein_35 methyltransferase domain-containing protein -
  L1A13_RS00260 (L1A13_00260) comYH 40815..41768 (+) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  L1A13_RS00265 (L1A13_00265) - 41819..43009 (+) 1191 WP_000167765.1 acetate kinase -
  L1A13_RS10345 - 43010..43141 (+) 132 WP_000768904.1 hypothetical protein -
  L1A13_RS00270 (L1A13_00270) rnpA 43158..43529 (+) 372 WP_000739244.1 ribonuclease P protein component -
  L1A13_RS00275 (L1A13_00275) - 43504..44328 (+) 825 WP_001809383.1 membrane protein insertase YidC -
  L1A13_RS00280 (L1A13_00280) jag 44347..45333 (+) 987 WP_000260014.1 RNA-binding cell elongation regulator Jag/EloR -
  L1A13_RS00285 (L1A13_00285) - 45384..46007 (+) 624 WP_000932635.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35718.89 Da        Isoelectric Point: 4.2474

>NTDB_id=646107 L1A13_RS00260 WP_000345099.1 40815..41768(+) (comYH) [Streptococcus pneumoniae strain CH2439]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=646107 L1A13_RS00260 WP_000345099.1 40815..41768(+) (comYH) [Streptococcus pneumoniae strain CH2439]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAGACTGAGCTAGAACAGGTCAAAGACAACAATC
AGACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTACTTTTGGTGTTTATTGTGGAAGAGCTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTTTGGGCGCTACTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTATTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539