Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG734_RS46150 Genome accession   NZ_CP107780
Coordinates   10587003..10587659 (+) Length   218 a.a.
NCBI ID   WP_330293365.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00576     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 10582003..10592659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG734_RS46135 (OG734_46185) - 10583971..10584999 (+) 1029 WP_330293362.1 SDR family oxidoreductase -
  OG734_RS46140 (OG734_46190) - 10585216..10585578 (-) 363 WP_330293363.1 hypothetical protein -
  OG734_RS46145 (OG734_46195) - 10585855..10587006 (+) 1152 WP_330293364.1 sensor histidine kinase -
  OG734_RS46150 (OG734_46200) vraR 10587003..10587659 (+) 657 WP_330293365.1 response regulator transcription factor Regulator
  OG734_RS46155 (OG734_46205) ligA 10587977..10590064 (-) 2088 WP_330293366.1 NAD-dependent DNA ligase LigA -
  OG734_RS46160 (OG734_46210) - 10590316..10590699 (+) 384 WP_330293367.1 helix-turn-helix domain-containing protein -
  OG734_RS46165 (OG734_46215) - 10590776..10592044 (-) 1269 WP_330293368.1 Tat pathway signal protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23123.61 Da        Isoelectric Point: 4.3753

>NTDB_id=646085 OG734_RS46150 WP_330293365.1 10587003..10587659(+) (vraR) [Streptomyces sp. NBC_00576]
MTTVLVVDDQFLIRAGLVGLLRAAPGIEVVGEASDGAEGVTLAARTAPDVILMDVRMPGMNGIEATERILARADDPPPRI
LMLTTFDLDEYVYGALRAGACGFLLKDSGPERLLAAVAAIAGGDALFAPSVTRRLVEAYARQTACEQPTDLDALTSRELE
VLTLIARGLSNLEIADRLYISEATVKTHLNRTMTKLDLDSRAQAVVVAYESGLVTPGG

Nucleotide


Download         Length: 657 bp        

>NTDB_id=646085 OG734_RS46150 WP_330293365.1 10587003..10587659(+) (vraR) [Streptomyces sp. NBC_00576]
ATGACCACAGTGCTTGTCGTGGACGACCAGTTCCTTATCCGGGCCGGCCTGGTGGGCCTGCTGCGTGCCGCACCCGGCAT
CGAGGTGGTCGGCGAGGCGAGCGACGGCGCGGAGGGCGTGACACTGGCCGCCCGGACCGCCCCAGACGTGATCCTCATGG
ATGTGCGGATGCCCGGCATGAACGGCATCGAGGCCACCGAACGTATTCTCGCCCGGGCCGATGACCCCCCGCCCCGGATC
CTGATGCTGACCACCTTCGACCTCGACGAGTATGTGTACGGGGCGCTGCGCGCCGGAGCCTGCGGGTTTCTGCTCAAGGA
CTCCGGCCCGGAGCGGCTGCTCGCCGCCGTGGCCGCGATCGCCGGTGGTGACGCGCTCTTCGCACCCAGCGTCACCCGCC
GCCTGGTGGAGGCTTACGCCCGGCAGACCGCCTGCGAACAGCCCACCGATCTGGACGCGTTGACCTCCCGTGAACTGGAG
GTCCTCACACTGATCGCACGCGGCCTGTCCAACCTGGAGATCGCTGACCGCCTCTACATCAGCGAGGCGACCGTCAAGAC
CCATCTCAACCGCACGATGACCAAACTGGACCTGGACAGCAGGGCACAGGCCGTGGTGGTGGCGTACGAATCGGGGCTGG
TGACCCCAGGCGGATAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(153-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.863

96.789

0.376
  degU Bacillus subtilis subsp. subtilis str. 168

36.607

100

0.376