Detailed information NTG0646073

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: L1A19_RS08945
• Genome accession: NZ_CP090888
• Coordinates: 1763999..1765036 (-)
• Length: 345 a.a.
• NCBI ID: WP_049479962.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PT8465
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1758999..1770036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
L1A19_RS08920 (L1A19_08920)	-	1759738..1761069 (-)	1332	WP_000390039.1	hemolysin family protein	-
L1A19_RS08925 (L1A19_08925)	endA	1761360..1762184 (-)	825	WP_001036787.1	DNA-entry nuclease EndA	Machinery gene
L1A19_RS08930 (L1A19_08930)	-	1762223..1762411 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
L1A19_RS08935 (L1A19_08935)	murA	1762404..1763687 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
L1A19_RS08940 (L1A19_08940)	-	1763711..1763941 (-)	231	WP_000250384.1	DUF1146 family protein	-
L1A19_RS08945 (L1A19_08945)	sepM	1763999..1765036 (-)	1038	WP_049479962.1	SepM family pheromone-processing serine protease	Regulator
L1A19_RS08950 (L1A19_08950)	coaD	1765020..1765508 (-)	489	WP_001280769.1	pantetheine-phosphate adenylyltransferase	-
L1A19_RS08955 (L1A19_08955)	rsmD	1765498..1766037 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
L1A19_RS08960 (L1A19_08960)	asnA	1766102..1767094 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
L1A19_RS08965 (L1A19_08965)	-	1767206..1767889 (-)	684	WP_001016910.1	Bax inhibitor-1/YccA family protein	-
L1A19_RS08970 (L1A19_08970)	-	1767945..1768685 (-)	741	WP_000152678.1	RNA methyltransferase	-
L1A19_RS08975 (L1A19_08975)	-	1768719..1768997 (+)	279	WP_001174613.1	acylphosphatase	-
L1A19_RS08980 (L1A19_08980)	yidC	1769075..1770001 (+)	927	WP_000835941.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37503.56 Da
• Isoelectric Point: 5.0724

>NTDB_id=646073 L1A19_RS08945 WP_049479962.1 1763999..1765036(-) (sepM) [Streptococcus pneumoniae strain PT8465]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQLYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=646073 L1A19_RS08945 WP_049479962.1 1763999..1765036(-) (sepM) [Streptococcus pneumoniae strain PT8465]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTATACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588