Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   L1A19_RS08925 Genome accession   NZ_CP090888
Coordinates   1761360..1762184 (-) Length   274 a.a.
NCBI ID   WP_001036787.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PT8465     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1756360..1767184
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A19_RS08920 (L1A19_08920) - 1759738..1761069 (-) 1332 WP_000390039.1 hemolysin family protein -
  L1A19_RS08925 (L1A19_08925) endA 1761360..1762184 (-) 825 WP_001036787.1 DNA-entry nuclease EndA Machinery gene
  L1A19_RS08930 (L1A19_08930) - 1762223..1762411 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  L1A19_RS08935 (L1A19_08935) murA 1762404..1763687 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  L1A19_RS08940 (L1A19_08940) - 1763711..1763941 (-) 231 WP_000250384.1 DUF1146 family protein -
  L1A19_RS08945 (L1A19_08945) sepM 1763999..1765036 (-) 1038 WP_049479962.1 SepM family pheromone-processing serine protease Regulator
  L1A19_RS08950 (L1A19_08950) coaD 1765020..1765508 (-) 489 WP_001280769.1 pantetheine-phosphate adenylyltransferase -
  L1A19_RS08955 (L1A19_08955) rsmD 1765498..1766037 (-) 540 WP_000706963.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  L1A19_RS08960 (L1A19_08960) asnA 1766102..1767094 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29917.60 Da        Isoelectric Point: 10.1197

>NTDB_id=646072 L1A19_RS08925 WP_001036787.1 1761360..1762184(-) (endA) [Streptococcus pneumoniae strain PT8465]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQGPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=646072 L1A19_RS08925 WP_001036787.1 1761360..1762184(-) (endA) [Streptococcus pneumoniae strain PT8465]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGGGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

98.905

100

0.989
  endA Streptococcus pneumoniae D39

98.905

100

0.989
  endA Streptococcus pneumoniae R6

98.905

100

0.989
  endA Streptococcus pneumoniae TIGR4

98.905

100

0.989