Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   L1A19_RS08880 Genome accession   NZ_CP090888
Coordinates   1744957..1745577 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain PT8465     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1739957..1750577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A19_RS08855 (L1A19_08855) recA 1740335..1741501 (-) 1167 WP_001085462.1 recombinase RecA Machinery gene
  L1A19_RS08860 (L1A19_08860) cinA 1741556..1742812 (-) 1257 WP_000642714.1 competence/damage-inducible protein A Machinery gene
  L1A19_RS08865 (L1A19_08865) - 1742896..1743912 (-) 1017 WP_000239282.1 LCP family protein -
  L1A19_RS08870 (L1A19_08870) - 1743920..1744438 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  L1A19_RS08875 (L1A19_08875) tsaE 1744428..1744871 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  L1A19_RS08880 (L1A19_08880) comM 1744957..1745577 (-) 621 WP_000839908.1 hypothetical protein Regulator
  L1A19_RS08885 (L1A19_08885) - 1745960..1746823 (-) 864 WP_001093617.1 helix-turn-helix transcriptional regulator -
  L1A19_RS10570 - 1747012..1747182 (+) 171 WP_000742179.1 PhrA family quorum-sensing system peptide -
  L1A19_RS08890 (L1A19_08890) - 1747632..1749647 (+) 2016 WP_000732392.1 DUF1430 domain-containing protein -
  L1A19_RS08895 (L1A19_08895) - 1749649..1750281 (+) 633 WP_000571410.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=646071 L1A19_RS08880 WP_000839908.1 1744957..1745577(-) (comM) [Streptococcus pneumoniae strain PT8465]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=646071 L1A19_RS08880 WP_000839908.1 1744957..1745577(-) (comM) [Streptococcus pneumoniae strain PT8465]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369