Detailed information NTG0645991

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: OG852_RS42135
• Genome accession: NZ_CP107772
• Coordinates: 9304705..9305370 (+)
• Length: 221 a.a.
• NCBI ID: WP_133913029.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00582
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 9299705..9310370

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG852_RS42105 (OG852_42130)	-	9299732..9300982 (+)	1251	WP_330350625.1	geranylgeranyl reductase family protein	-
OG852_RS42110 (OG852_42135)	-	9301010..9301462 (-)	453	WP_133913024.1	nitroreductase family deazaflavin-dependent oxidoreductase	-
OG852_RS42115 (OG852_42140)	-	9301609..9302301 (+)	693	WP_133913025.1	TetR/AcrR family transcriptional regulator	-
OG852_RS42120 (OG852_42145)	-	9302327..9302854 (-)	528	WP_133913026.1	MarR family transcriptional regulator	-
OG852_RS42125 (OG852_42150)	-	9302926..9303360 (+)	435	WP_133913027.1	winged helix-turn-helix transcriptional regulator	-
OG852_RS42130 (OG852_42155)	-	9303512..9304708 (+)	1197	WP_133913028.1	sensor histidine kinase	-
OG852_RS42135 (OG852_42160)	vraR	9304705..9305370 (+)	666	WP_133913029.1	response regulator transcription factor	Regulator
OG852_RS42140 (OG852_42165)	-	9305482..9306981 (-)	1500	WP_330350626.1	MFS transporter	-
OG852_RS42145 (OG852_42170)	-	9307068..9307490 (+)	423	WP_133913031.1	MarR family transcriptional regulator	-
OG852_RS42150 (OG852_42175)	-	9307477..9308232 (-)	756	WP_330350627.1	maleylpyruvate isomerase family mycothiol-dependent enzyme	-
OG852_RS42155 (OG852_42180)	-	9308317..9308643 (-)	327	Protein_8335	MFS transporter	-
OG852_RS42160 (OG852_42185)	-	9308838..9309581 (+)	744	WP_330350628.1	GntR family transcriptional regulator	-
OG852_RS42165 (OG852_42190)	-	9309643..9309906 (-)	264	Protein_8337	SDR family NAD(P)-dependent oxidoreductase	-
OG852_RS42170 (OG852_42195)	-	9309852..9310217 (-)	366	WP_330351594.1	SDR family NAD(P)-dependent oxidoreductase	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 23941.73 Da
• Isoelectric Point: 5.0242

>NTDB_id=645991 OG852_RS42135 WP_133913029.1 9304705..9305370(+) (vraR) [Streptomyces sp. NBC_00582]
MIRVLLADDQSLVRAGFRALLDAQPDIEVCGEAADGEEAVRGVRALRPDVVLMDIRMPVLDGLAATRRITGDAALAQVRV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVAGDALLSPGVTRRLIAEFAARSKEPAAADELSRLTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide

• Length: 666 bp

>NTDB_id=645991 OG852_RS42135 WP_133913029.1 9304705..9305370(+) (vraR) [Streptomyces sp. NBC_00582]
GTGATCCGTGTGCTGCTCGCCGACGACCAGTCCCTGGTCAGGGCGGGATTCCGGGCGTTGCTCGACGCGCAGCCGGACAT
CGAGGTGTGCGGGGAGGCCGCCGACGGCGAGGAGGCGGTGCGCGGGGTCCGCGCGCTGCGTCCGGACGTCGTCCTGATGG
ACATCCGCATGCCGGTGCTGGACGGGCTGGCGGCCACCCGCCGGATCACCGGGGACGCGGCGCTCGCCCAGGTCAGGGTG
GTCATGCTGACCACGTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGGTCCGGGGCCTCGGGCTTTCTGGTCAAGGA
CACCGAACCCGAGGAGCTCCTGCGTGCCGTACGGGCGGTGGTGGCCGGTGACGCGCTGCTCTCGCCCGGCGTGACGCGGC
GGCTCATCGCCGAGTTCGCCGCCCGCTCCAAGGAGCCCGCCGCGGCGGACGAGTTGAGCCGCCTCACGGAACGCGAACGG
GAGGTGATGGCCCTGGTCGGCATCGGCCTGTCCAACGAGGAGATCGCCCGCCGCCTGGTCGTCAGCCCCCTCACCGCGAA
GACCCACGTCAGCCGCACGATGGTCAAGTTGGGCGCCCGCGACCGCGCCCAACTGGTCGTCCTGGCCTACGAGTCGGGGC
TGGTCCGCCCGGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-117)

• Bacterial regulatory proteins, luxR family (GerE) (155-209)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	37.674	97.285	0.367
degU	Bacillus subtilis subsp. subtilis str. 168	35.556	100	0.362