Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   L1A18_RS01705 Genome accession   NZ_CP090887
Coordinates   330295..330984 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP7536     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 325295..335984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A18_RS01680 (L1A18_01680) gpsB 325404..325733 (+) 330 WP_000146522.1 cell division regulator GpsB -
  L1A18_RS01690 (L1A18_01690) - 326219..327376 (+) 1158 WP_000711393.1 class I SAM-dependent RNA methyltransferase -
  L1A18_RS01695 (L1A18_01695) mapZ 327389..328783 (+) 1395 WP_000039274.1 mid-cell-anchored protein MapZ -
  L1A18_RS01700 (L1A18_01700) gndA 328859..330283 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  L1A18_RS01705 (L1A18_01705) covR 330295..330984 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  L1A18_RS01710 (L1A18_01710) cbpC 331083..332105 (+) 1023 WP_000771086.1 choline-binding protein CbpC -
  L1A18_RS01715 (L1A18_01715) - 332124..333245 (+) 1122 WP_000771140.1 N-acetylmuramoyl-L-alanine amidase family protein -
  L1A18_RS01720 (L1A18_01720) - 333363..334595 (-) 1233 WP_000765691.1 MFS transporter -
  L1A18_RS01725 (L1A18_01725) - 334638..335513 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=645960 L1A18_RS01705 WP_000518011.1 330295..330984(+) (covR) [Streptococcus pneumoniae strain NP7536]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=645960 L1A18_RS01705 WP_000518011.1 330295..330984(+) (covR) [Streptococcus pneumoniae strain NP7536]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAATG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467