Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   L1A17_RS03820 Genome accession   NZ_CP090886
Coordinates   757538..757840 (+) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NP7513     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 752538..762840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A17_RS03790 (L1A17_03790) - 753295..754353 (+) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  L1A17_RS03795 (L1A17_03795) - 754504..754869 (+) 366 WP_000286415.1 DUF1033 family protein -
  L1A17_RS03800 (L1A17_03800) comGA/cglA/cilD 754945..755886 (+) 942 WP_000249552.1 competence type IV pilus ATPase ComGA Machinery gene
  L1A17_RS03805 (L1A17_03805) comGB/cglB 755834..756850 (+) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  L1A17_RS03810 (L1A17_03810) comGC/cglC 756852..757178 (+) 327 WP_000738636.1 comG operon protein ComGC Machinery gene
  L1A17_RS03815 (L1A17_03815) comGD/cglD 757171..757575 (+) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  L1A17_RS03820 (L1A17_03820) comGE/cglE 757538..757840 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  L1A17_RS03825 (L1A17_03825) comGF/cglF 757803..758264 (+) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  L1A17_RS03830 (L1A17_03830) comGG/cglG 758242..758655 (+) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  L1A17_RS03835 (L1A17_03835) - 758792..759386 (+) 595 Protein_742 methyltransferase domain-containing protein -
  L1A17_RS03840 (L1A17_03840) comYH 759447..760400 (+) 954 WP_000345099.1 class I SAM-dependent methyltransferase Machinery gene
  L1A17_RS03845 (L1A17_03845) - 760451..761641 (+) 1191 WP_000167765.1 acetate kinase -
  L1A17_RS10585 - 761642..761773 (+) 132 WP_000768904.1 hypothetical protein -
  L1A17_RS03850 (L1A17_03850) rnpA 761790..762161 (+) 372 WP_000739244.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=645909 L1A17_RS03820 WP_000413382.1 757538..757840(+) (comGE/cglE) [Streptococcus pneumoniae strain NP7513]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=645909 L1A17_RS03820 WP_000413382.1 757538..757840(+) (comGE/cglE) [Streptococcus pneumoniae strain NP7513]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4