Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN38_RS11215 Genome accession   NZ_CP107765
Coordinates   2473285..2473968 (-) Length   227 a.a.
NCBI ID   WP_242707769.1    Uniprot ID   A0ABS9X7S8
Organism   Streptomyces sp. NBC_00588     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2468285..2478968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN38_RS11190 (OHN38_11180) - 2468506..2469369 (-) 864 WP_016432207.1 ABC transporter permease -
  OHN38_RS11195 (OHN38_11185) - 2469359..2470174 (-) 816 WP_016432208.1 ABC transporter ATP-binding protein -
  OHN38_RS11200 (OHN38_11190) - 2470336..2471028 (+) 693 WP_016432209.1 response regulator -
  OHN38_RS11205 (OHN38_11195) - 2471066..2472658 (-) 1593 WP_242707771.1 cation acetate symporter -
  OHN38_RS11210 (OHN38_11200) - 2472655..2473215 (-) 561 WP_330282059.1 DUF485 domain-containing protein -
  OHN38_RS11215 (OHN38_11205) vraR 2473285..2473968 (-) 684 WP_242707769.1 response regulator transcription factor Regulator
  OHN38_RS11220 (OHN38_11210) - 2473965..2475116 (-) 1152 WP_242707768.1 sensor histidine kinase -
  OHN38_RS11225 (OHN38_11215) - 2475113..2475637 (-) 525 WP_242707767.1 CcdC protein domain-containing protein -
  OHN38_RS11230 (OHN38_11220) - 2475952..2478075 (-) 2124 WP_242707766.1 DNA topoisomerase IV subunit B -
  OHN38_RS11235 (OHN38_11225) - 2478519..2478749 (+) 231 WP_016432216.1 hypothetical protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 24250.72 Da        Isoelectric Point: 5.1668

>NTDB_id=645836 OHN38_RS11215 WP_242707769.1 2473285..2473968(-) (vraR) [Streptomyces sp. NBC_00588]
MTEGAEDRPARVVVADDQTVVREGIVMLLGLLPGIEVVGAAGDGFEAVRLVAELAPDVVLMDLRMPRCDGVEATRRIRAE
HPGTQVVVLTTYADDDSLFPALRAGARGYLTKDAGGDEIVRAVRSVLSGDAGLSPSIQRRLLERLSGPEPQPAVETEAPD
GLTTRETEVLLLIAEGLSNQEIARRLHVSTATVKTHINNLFAKTGLKDRAQAVRYAYAKGLARPPVG

Nucleotide


Download         Length: 684 bp        

>NTDB_id=645836 OHN38_RS11215 WP_242707769.1 2473285..2473968(-) (vraR) [Streptomyces sp. NBC_00588]
ATGACCGAAGGGGCCGAGGACAGGCCTGCGCGAGTGGTGGTCGCGGACGACCAGACGGTGGTGCGTGAGGGCATCGTGAT
GCTGCTGGGCCTGCTGCCCGGGATCGAGGTGGTCGGGGCCGCGGGGGACGGGTTCGAGGCGGTGCGGCTCGTCGCCGAAC
TCGCTCCGGACGTGGTGCTGATGGACCTGCGCATGCCGCGTTGCGACGGCGTGGAGGCGACCCGGCGGATCCGCGCCGAA
CACCCGGGCACTCAGGTCGTGGTGCTCACGACGTACGCGGACGACGACTCGCTGTTCCCGGCGCTGCGAGCGGGGGCGCG
GGGCTATCTCACCAAGGACGCGGGCGGGGACGAGATCGTACGGGCCGTGCGGAGCGTGCTGTCCGGGGACGCGGGGCTGT
CGCCGAGCATCCAACGGCGGCTGCTGGAGCGGCTGTCCGGTCCCGAGCCGCAGCCGGCTGTCGAGACCGAGGCGCCGGAC
GGGCTCACCACGCGTGAGACCGAGGTCCTGCTGCTGATCGCCGAGGGGCTCAGCAACCAGGAGATCGCCCGCAGACTGCA
TGTCTCCACGGCGACGGTGAAGACCCACATCAACAACCTCTTCGCCAAGACGGGGCTCAAGGACCGTGCGCAGGCGGTGC
GTTACGCGTACGCGAAGGGGCTCGCGCGGCCACCGGTGGGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-123)

Bacterial regulatory proteins, luxR family (GerE)

(161-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.437

93.833

0.37
  degU Bacillus subtilis subsp. subtilis str. 168

37.387

97.797

0.366