Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG974_RS19785 Genome accession   NZ_CP107757
Coordinates   4428536..4429159 (+) Length   207 a.a.
NCBI ID   WP_327284029.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00597     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4423536..4434159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG974_RS19760 (OG974_19750) - 4423819..4424394 (+) 576 WP_327284025.1 TerD family protein -
  OG974_RS19765 (OG974_19755) - 4424484..4424999 (+) 516 WP_327284026.1 GNAT family N-acetyltransferase -
  OG974_RS19770 (OG974_19760) - 4425006..4426415 (-) 1410 WP_371643923.1 M1 family metallopeptidase -
  OG974_RS19775 (OG974_19765) - 4426513..4427070 (-) 558 WP_327284028.1 heme-binding protein -
  OG974_RS19780 (OG974_19770) - 4427202..4428539 (+) 1338 WP_371643925.1 sensor histidine kinase -
  OG974_RS19785 (OG974_19775) vraR 4428536..4429159 (+) 624 WP_327284029.1 response regulator transcription factor Regulator
  OG974_RS19790 (OG974_19780) - 4429297..4430460 (+) 1164 WP_371643927.1 M4 family metallopeptidase -
  OG974_RS19795 (OG974_19785) - 4430669..4431172 (+) 504 WP_327284031.1 hypothetical protein -
  OG974_RS19800 (OG974_19790) - 4431400..4432074 (-) 675 WP_327284032.1 pentapeptide repeat-containing protein -
  OG974_RS19805 (OG974_19795) - 4432186..4433178 (+) 993 WP_327285696.1 zinc-binding dehydrogenase -
  OG974_RS19810 (OG974_19800) - 4433241..4433744 (+) 504 WP_328763104.1 FBP domain-containing protein -
  OG974_RS19815 (OG974_19805) - 4433791..4433916 (-) 126 Protein_3912 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 21776.98 Da        Isoelectric Point: 5.5991

>NTDB_id=645696 OG974_RS19785 WP_327284029.1 4428536..4429159(+) (vraR) [Streptomyces sp. NBC_00597]
MTTTILLCDDHAVVRAGLLALLGSAPDIEVLGEAGSGEEAVALAAKLHPDVVLMDLQLGEGIDGVEATRRITAVTDPPHV
LVLTTYDTDADVTRAIAAGATGYLLKAERPEELFSAIHSAAAGRTTLSAPVASRVMAHMRGSRPTLTDRELDILGQLARG
LGNRDIARALFISEATVKTHLGRIYDKLGVETRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 624 bp        

>NTDB_id=645696 OG974_RS19785 WP_327284029.1 4428536..4429159(+) (vraR) [Streptomyces sp. NBC_00597]
ATGACGACGACGATCCTGCTCTGCGACGACCACGCCGTGGTCCGCGCCGGCCTGCTGGCACTGCTGGGCAGCGCACCGGA
CATCGAGGTCCTGGGCGAGGCGGGCAGCGGCGAGGAGGCGGTGGCCCTGGCCGCGAAGCTGCACCCGGACGTGGTGCTGA
TGGACCTCCAGCTGGGCGAGGGCATCGACGGCGTCGAGGCCACCCGCCGCATCACGGCGGTGACCGACCCCCCGCACGTA
CTCGTCCTCACGACGTACGACACGGACGCGGACGTCACCCGGGCCATCGCGGCGGGCGCCACGGGCTACCTGCTGAAGGC
GGAGCGCCCGGAGGAGCTGTTCTCCGCGATCCACTCGGCGGCGGCGGGCCGCACCACGCTCTCCGCGCCGGTGGCGAGCC
GTGTGATGGCCCACATGCGGGGCTCGCGCCCGACGCTGACGGACCGCGAGCTGGACATCCTGGGCCAGCTGGCGCGGGGG
CTGGGCAACCGGGACATCGCACGGGCCCTGTTCATCAGCGAGGCCACGGTCAAGACCCACCTGGGCCGCATCTACGACAA
GCTCGGCGTGGAGACCCGCGCGGGAGCGGTCTCCGTGGCGAAGGAGCAGCGCCTCCTGCCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(145-200)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.048

100

0.396
  degU Bacillus subtilis subsp. subtilis str. 168

35.023

100

0.367