Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG974_RS11055 Genome accession   NZ_CP107757
Coordinates   2515857..2516486 (+) Length   209 a.a.
NCBI ID   WP_327282522.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00597     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2510857..2521486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG974_RS11035 (OG974_11030) - 2512152..2512766 (-) 615 WP_327282518.1 vitamin K epoxide reductase family protein -
  OG974_RS11040 (OG974_11035) - 2512903..2513784 (+) 882 WP_327282519.1 ABC transporter ATP-binding protein -
  OG974_RS11045 (OG974_11040) - 2513781..2514635 (+) 855 WP_327282520.1 ABC transporter permease -
  OG974_RS11050 (OG974_11045) - 2514593..2515843 (+) 1251 WP_328762175.1 sensor histidine kinase -
  OG974_RS11055 (OG974_11050) vraR 2515857..2516486 (+) 630 WP_327282522.1 response regulator transcription factor Regulator
  OG974_RS11060 (OG974_11055) hisS 2516620..2517879 (-) 1260 WP_327282523.1 histidine--tRNA ligase -
  OG974_RS11065 (OG974_11060) - 2517890..2518603 (-) 714 WP_327282524.1 MBL fold metallo-hydrolase -
  OG974_RS11070 (OG974_11065) - 2518768..2519550 (+) 783 WP_327282525.1 peptidylprolyl isomerase -
  OG974_RS11075 (OG974_11070) - 2519742..2520971 (+) 1230 WP_327282526.1 DUF349 domain-containing protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 22438.00 Da        Isoelectric Point: 5.4136

>NTDB_id=645671 OG974_RS11055 WP_327282522.1 2515857..2516486(+) (vraR) [Streptomyces sp. NBC_00597]
MIRILLADDHPVVREGLRGMLSAEPDLEVVAEAANGPQAEALAAELLPGGLDLILMDLRMPGGDGVESIARISAAGLPVR
VVVLTTYENDRDILRAVEAGAAGYLLKDMARAELAEAVRAAVRGETVLAPSVAGRLVDRLRTRPERPRLSDREVAVLRLV
AEGATNAEIGRRLFVAESTVKTHLLRIFGKLEVTDRTAAVTTAMRHDLL

Nucleotide


Download         Length: 630 bp        

>NTDB_id=645671 OG974_RS11055 WP_327282522.1 2515857..2516486(+) (vraR) [Streptomyces sp. NBC_00597]
ATGATCCGCATCCTGCTGGCCGACGACCACCCCGTGGTACGGGAAGGCCTGCGCGGCATGCTCAGTGCGGAGCCGGACCT
GGAGGTCGTCGCGGAGGCCGCGAACGGCCCGCAGGCCGAGGCACTGGCCGCGGAGCTGCTCCCCGGCGGCCTGGACCTGA
TCCTGATGGACCTGCGGATGCCGGGCGGCGACGGCGTCGAGTCCATCGCCCGGATCAGCGCGGCCGGGCTGCCGGTGCGG
GTCGTCGTCCTGACGACGTACGAGAACGACCGGGACATCCTGCGGGCGGTGGAAGCGGGGGCCGCCGGCTACTTGTTGAA
GGACATGGCACGGGCCGAACTGGCCGAGGCCGTCCGTGCGGCGGTGCGTGGCGAGACGGTCCTGGCCCCGTCGGTGGCGG
GCCGCCTGGTCGACCGCCTCCGCACCCGCCCCGAGCGTCCGCGCCTGTCCGACCGCGAGGTCGCGGTCCTGCGCCTCGTC
GCGGAGGGCGCGACGAACGCGGAGATCGGCCGGCGCCTGTTCGTGGCGGAGTCCACGGTCAAGACGCACCTGCTGCGCAT
CTTCGGAAAACTGGAGGTCACGGACCGCACGGCGGCGGTGACCACGGCCATGCGCCACGACCTCCTCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-119)

Bacterial regulatory proteins, luxR family (GerE)

(149-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

42.105

100

0.421
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.373