Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG888_RS07950 Genome accession   NZ_CP107749
Coordinates   1735363..1736028 (-) Length   221 a.a.
NCBI ID   WP_327669121.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00622     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1730363..1741028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG888_RS07925 (OG888_07915) - 1730437..1731288 (-) 852 WP_327669118.1 class II fructose-bisphosphate aldolase -
  OG888_RS07930 (OG888_07920) - 1731323..1732240 (-) 918 WP_327669119.1 SIS domain-containing protein -
  OG888_RS07935 (OG888_07925) - 1732433..1733212 (+) 780 WP_266716230.1 DeoR/GlpR family DNA-binding transcription regulator -
  OG888_RS07940 (OG888_07930) - 1733309..1734520 (+) 1212 WP_371590727.1 MFS transporter -
  OG888_RS07945 (OG888_07935) - 1734592..1735341 (+) 750 WP_327669120.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OG888_RS07950 (OG888_07940) vraR 1735363..1736028 (-) 666 WP_327669121.1 response regulator transcription factor Regulator
  OG888_RS07955 (OG888_07945) - 1736025..1737278 (-) 1254 WP_327669122.1 sensor histidine kinase -
  OG888_RS07960 (OG888_07950) - 1737357..1738082 (-) 726 WP_327669123.1 TetR/AcrR family transcriptional regulator -
  OG888_RS07965 (OG888_07955) - 1738231..1738689 (+) 459 WP_327664777.1 nitroreductase/quinone reductase family protein -
  OG888_RS07970 (OG888_07960) - 1738724..1739962 (-) 1239 WP_371590728.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24063.83 Da        Isoelectric Point: 4.7261

>NTDB_id=645463 OG888_RS07950 WP_327669121.1 1735363..1736028(-) (vraR) [Streptomyces sp. NBC_00622]
MIRVLLADDQSLVRAGFRALLDAQSDIEVAGEAADGEEAVRLVRELRPDVVLMDIRMPLLDGLAATRRIGADADLEAVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVHGDALLSPGVTRRLIAEFAARSKEPATVAPLDELTERER
EVMALVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=645463 OG888_RS07950 WP_327669121.1 1735363..1736028(-) (vraR) [Streptomyces sp. NBC_00622]
GTGATCCGCGTACTGCTCGCCGACGACCAGTCGCTCGTCCGCGCCGGGTTCCGGGCGCTGCTCGACGCGCAGAGCGACAT
CGAGGTCGCGGGCGAGGCGGCGGACGGCGAGGAAGCGGTGCGCCTGGTGCGCGAACTCCGTCCCGACGTCGTACTCATGG
ACATCCGCATGCCGCTGCTCGACGGCCTCGCGGCGACCCGCCGGATCGGCGCGGACGCCGACCTGGAGGCGGTGAAGGTG
GTCATGCTCACCACCTTCGAACTCGACGAGTACGTCTTCGAGGCCATCCGCTCCGGAGCCTCCGGGTTCCTCGTCAAGGA
CACCGAGCCGGAGGAACTGCTGCGCGCCGTAAGGGCAGTTGTCCATGGCGACGCGCTGCTCTCGCCTGGCGTCACCCGCC
GCCTGATCGCCGAGTTCGCGGCGCGCTCGAAGGAGCCGGCGACCGTCGCGCCGCTCGACGAACTGACGGAACGGGAGCGG
GAGGTGATGGCGCTCGTCGGCATCGGCCTGTCCAACGAGGAGATCGCCCGCCGCCTCGTCGTCAGCCCACTCACCGCGAA
GACCCATGTGAGCCGCACGATGGTGAAGCTGGGCGCCCGCGACCGGGCCCAACTGGTCGTCCTGGCCTATGAGTCGGGGC
TCGTGCGGCCGGGGTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(154-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

97.285

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.371