Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN35_RS20905 Genome accession   NZ_CP107748
Coordinates   4632599..4633225 (+) Length   208 a.a.
NCBI ID   WP_326814796.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00623     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4627599..4638225
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN35_RS20885 (OHN35_20910) - 4628393..4629793 (-) 1401 WP_326628421.1 M1 family metallopeptidase -
  OHN35_RS20890 (OHN35_20915) - 4629841..4630443 (-) 603 WP_267003484.1 ankyrin repeat domain-containing protein -
  OHN35_RS20895 (OHN35_20920) - 4630476..4631033 (-) 558 WP_326628424.1 heme-binding protein -
  OHN35_RS20900 (OHN35_20925) - 4631286..4632602 (+) 1317 WP_406309801.1 sensor histidine kinase -
  OHN35_RS20905 (OHN35_20930) vraR 4632599..4633225 (+) 627 WP_326814796.1 response regulator transcription factor Regulator
  OHN35_RS20910 (OHN35_20935) - 4633344..4633841 (+) 498 WP_267003488.1 hypothetical protein -
  OHN35_RS20915 (OHN35_20940) - 4633869..4634570 (-) 702 WP_326814795.1 pentapeptide repeat-containing protein -
  OHN35_RS20920 (OHN35_20945) - 4634670..4635869 (+) 1200 WP_326814794.1 NAD(P)-binding protein -
  OHN35_RS20925 (OHN35_20950) - 4635916..4636917 (+) 1002 WP_327239964.1 zinc-binding dehydrogenase -
  OHN35_RS20930 (OHN35_20955) - 4636935..4637408 (-) 474 WP_267003496.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 208 a.a.        Molecular weight: 22054.35 Da        Isoelectric Point: 5.1096

>NTDB_id=645408 OHN35_RS20905 WP_326814796.1 4632599..4633225(+) (vraR) [Streptomyces sp. NBC_00623]
MTPPAVRILLCDDHAVVRAGLLALLGSEPDIEVVGEAGSGEEAVALAARLTPDVVLMDLQLGEGIDGAEATRRIAVTGVH
VLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSPPVASRVMARMRSPLPTLTDRERDILGQLSQ
GLGNREIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 627 bp        

>NTDB_id=645408 OHN35_RS20905 WP_326814796.1 4632599..4633225(+) (vraR) [Streptomyces sp. NBC_00623]
ATGACCCCGCCCGCCGTACGGATCCTGCTCTGCGACGACCACGCCGTCGTACGCGCCGGACTGCTCGCCCTCCTGGGCAG
CGAACCGGACATCGAGGTCGTCGGCGAGGCGGGCAGCGGCGAGGAGGCCGTCGCCCTGGCCGCCCGGCTGACCCCGGACG
TCGTCCTGATGGACCTCCAACTGGGCGAAGGAATCGACGGCGCCGAAGCCACCCGCCGCATCGCGGTCACCGGCGTCCAT
GTCCTCGTCCTCACGACGTACGACACGGACGCCGACATCACCCGCGCCATCGAAGCGGGCGCCACCGGCTACCTGCTGAA
GGCGGAACGCCCGGAGGAACTGTTCGCCGCGATCCGCTCGGCGGCCCAGGGCCGCACCACGCTCTCCCCACCGGTTGCCA
GCCGTGTCATGGCCCGCATGCGCAGCCCCCTGCCGACGCTCACGGACCGCGAACGCGACATCCTGGGCCAGCTGTCCCAG
GGCCTGGGCAACCGGGAGATCGCCCGGGCCCTGTTCATCAGCGAGGCCACGGTCAAGACGCATCTGGGCCGCATCTATGA
CAAACTCGGCGTCGACACCCGCGCGGGCGCCGTGTCCGTGGCGAAGGAGCAGCGGCTGCTGCCGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(146-201)

Response regulator receiver domain (Response_reg)

(8-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.614

99.519

0.394
  degU Bacillus subtilis subsp. subtilis str. 168

35.321

100

0.37