Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN15_RS37145 Genome accession   NZ_CP107746
Coordinates   8399061..8399696 (+) Length   211 a.a.
NCBI ID   WP_327128635.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00624     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8394061..8404696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN15_RS37120 (OHN15_37185) - 8395032..8395364 (-) 333 WP_406296286.1 DUF6233 domain-containing protein -
  OHN15_RS37125 (OHN15_37190) - 8395367..8395708 (-) 342 WP_406296288.1 hypothetical protein -
  OHN15_RS37130 (OHN15_37195) - 8395905..8396588 (-) 684 WP_406296290.1 ABC transporter ATP-binding protein -
  OHN15_RS37135 (OHN15_37200) - 8396585..8397673 (-) 1089 WP_406297109.1 ABC transporter permease -
  OHN15_RS37140 (OHN15_37205) - 8397844..8399064 (+) 1221 WP_371794355.1 sensor histidine kinase -
  OHN15_RS37145 (OHN15_37210) vraR 8399061..8399696 (+) 636 WP_327128635.1 response regulator transcription factor Regulator
  OHN15_RS37150 - 8399778..8400050 (-) 273 WP_327128636.1 hypothetical protein -
  OHN15_RS37155 (OHN15_37215) - 8400065..8400703 (-) 639 WP_327128637.1 maleylpyruvate isomerase N-terminal domain-containing protein -
  OHN15_RS37160 (OHN15_37220) - 8401095..8401358 (+) 264 WP_327128638.1 hypothetical protein -
  OHN15_RS37165 (OHN15_37225) - 8401361..8401732 (+) 372 WP_371797191.1 fic family toxin-antitoxin system, toxin component -
  OHN15_RS37170 (OHN15_37230) - 8401995..8402723 (+) 729 WP_406296294.1 type 1 glutamine amidotransferase -
  OHN15_RS37175 (OHN15_37235) - 8402683..8403153 (-) 471 WP_406297111.1 benzoate/H(+) symporter BenE family transporter -
  OHN15_RS37180 - 8403161..8403382 (-) 222 Protein_7346 SDR family NAD(P)-dependent oxidoreductase -
  OHN15_RS37185 (OHN15_37240) - 8403839..8404600 (+) 762 WP_327129308.1 DeoR/GlpR family DNA-binding transcription regulator -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 22179.42 Da        Isoelectric Point: 6.2573

>NTDB_id=645366 OHN15_RS37145 WP_327128635.1 8399061..8399696(+) (vraR) [Streptomyces sp. NBC_00624]
MTDTPIRLLLADDHPVVRAGLRAVLETEAGIEVVAEAPTAEDAVARAAQGDIDVVLMDLQFGKGMNGAEATAAITARPRA
PRVLIVTTYDTDADTLRAIEAGATGYLLKDAPPEDLAAAVRTAAAGRTTLAPTVADRLMNRLRTPGTTLTRRETEVLALV
AVGLSNQAIGNRLHLTEGTVKSHLARIYVKLGVDSRTAAVATATELGLIRR

Nucleotide


Download         Length: 636 bp        

>NTDB_id=645366 OHN15_RS37145 WP_327128635.1 8399061..8399696(+) (vraR) [Streptomyces sp. NBC_00624]
GTGACCGACACCCCCATCCGCCTGCTCCTGGCCGACGACCACCCCGTCGTGCGGGCAGGGCTGCGCGCCGTGCTGGAGAC
CGAAGCCGGCATCGAAGTGGTGGCCGAAGCCCCGACCGCCGAGGACGCCGTCGCCCGTGCCGCCCAGGGCGACATCGATG
TCGTCCTCATGGACCTTCAGTTCGGGAAGGGAATGAACGGCGCCGAAGCCACCGCCGCGATCACCGCACGCCCTCGAGCC
CCCCGCGTGTTGATCGTCACCACCTACGACACCGACGCCGACACTCTCCGCGCCATCGAAGCCGGCGCCACCGGCTACCT
CCTCAAGGACGCCCCACCCGAGGATCTGGCCGCCGCCGTACGCACCGCTGCGGCAGGCCGCACCACACTGGCACCCACCG
TCGCGGACCGGTTGATGAACCGGCTGCGCACTCCCGGCACCACCCTGACCCGGCGCGAGACCGAAGTTCTCGCACTGGTC
GCCGTGGGCCTGTCCAACCAGGCCATCGGAAACCGGCTCCACCTCACCGAAGGAACGGTCAAGTCCCACCTGGCCCGCAT
CTACGTCAAACTCGGCGTCGACTCCCGCACCGCTGCCGTCGCCACAGCCACCGAACTCGGCCTCATCCGGCGATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(9-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.462

98.578

0.379
  degU Bacillus subtilis subsp. subtilis str. 168

33.628

100

0.36