Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN15_RS09030 Genome accession   NZ_CP107746
Coordinates   2049551..2050195 (-) Length   214 a.a.
NCBI ID   WP_030920215.1    Uniprot ID   A0ABV2U2Y5
Organism   Streptomyces sp. NBC_00624     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2044551..2055195
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN15_RS09000 (OHN15_09045) - 2045070..2045576 (+) 507 WP_030920231.1 HNH endonuclease -
  OHN15_RS09005 (OHN15_09050) - 2045746..2046675 (-) 930 WP_277325434.1 SPFH domain-containing protein -
  OHN15_RS09010 (OHN15_09055) - 2046802..2047230 (-) 429 WP_093772011.1 NfeD family protein -
  OHN15_RS09015 (OHN15_09060) - 2047285..2048082 (-) 798 WP_030920222.1 ABC transporter ATP-binding protein -
  OHN15_RS09020 (OHN15_09065) - 2048206..2048988 (+) 783 WP_371796497.1 hypothetical protein -
  OHN15_RS09025 (OHN15_09070) - 2049155..2049403 (-) 249 WP_030920217.1 chaplin family protein -
  OHN15_RS09030 (OHN15_09075) vraR 2049551..2050195 (-) 645 WP_030920215.1 response regulator transcription factor Regulator
  OHN15_RS09035 (OHN15_09080) - 2050188..2051333 (-) 1146 WP_327124202.1 GAF domain-containing sensor histidine kinase -
  OHN15_RS09040 (OHN15_09085) - 2051526..2052269 (+) 744 WP_406292431.1 SDR family NAD(P)-dependent oxidoreductase -
  OHN15_RS09045 (OHN15_09090) - 2052266..2053370 (+) 1105 Protein_1794 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OHN15_RS09050 (OHN15_09095) - 2053658..2054407 (+) 750 WP_327124205.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23018.29 Da        Isoelectric Point: 5.1544

>NTDB_id=645299 OHN15_RS09030 WP_030920215.1 2049551..2050195(-) (vraR) [Streptomyces sp. NBC_00624]
MADKIIRVLLVDDHQVVRRGLRTFLEIQDDIEVVGEAADGAEGVARSEELHPDVVLMDIKMPGTDGIEALRKLRELENPA
KVLIVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIRSVYAGHVLLQPEVAGALLAQEDAGGGTGRGSTLTDREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLSDRTQAALWAVRHGVAG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=645299 OHN15_RS09030 WP_030920215.1 2049551..2050195(-) (vraR) [Streptomyces sp. NBC_00624]
GTGGCTGACAAGATCATCAGGGTGCTGCTGGTCGACGACCACCAGGTGGTCCGCCGCGGTCTGCGTACGTTCCTGGAGAT
CCAGGACGACATAGAGGTCGTCGGCGAGGCGGCCGACGGCGCGGAGGGTGTTGCCAGGAGCGAGGAGCTGCACCCCGACG
TGGTCCTGATGGACATCAAGATGCCGGGCACCGACGGCATCGAGGCGCTCCGCAAGCTCCGGGAGCTGGAGAACCCGGCC
AAGGTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTCCCGGCCCTGCGCGCGGGTGCCTCCGGTTACGTGTA
CAAGGACGTCGACCCGGACGCACTGGCCGGCGCCATCCGCTCGGTGTACGCGGGCCATGTCCTGCTCCAGCCGGAGGTCG
CCGGAGCCCTGCTCGCCCAGGAGGACGCCGGCGGTGGCACGGGCCGCGGGAGCACTCTCACCGACCGGGAGCGGGAGGTG
CTGGGCCTGATCGCCGACGGCCGTTCCAACCGTGAGATCGCCCGGGCGTTGGTCCTCTCGGAGAAGACCGTCAAGACGCA
CGTCTCGAACATTCTGATGAAGCTGGATCTGTCGGACCGTACCCAGGCCGCCCTTTGGGCCGTCCGGCATGGGGTGGCAG
GCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.444

96.729

0.43
  degU Bacillus subtilis subsp. subtilis str. 168

39.819

100

0.411