Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OHN15_RS04420 Genome accession   NZ_CP107746
Coordinates   1007982..1008647 (-) Length   221 a.a.
NCBI ID   WP_327123260.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00624     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1002982..1013647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OHN15_RS04390 (OHN15_04425) - 1003065..1004282 (+) 1218 WP_327123255.1 MFS transporter -
  OHN15_RS04395 (OHN15_04430) - 1004404..1004772 (+) 369 WP_327123256.1 SCO4225 family membrane protein -
  OHN15_RS04400 (OHN15_04435) - 1004794..1005555 (+) 762 WP_327123257.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  OHN15_RS04405 (OHN15_04440) - 1005600..1006001 (-) 402 WP_030920900.1 MarR family winged helix-turn-helix transcriptional regulator -
  OHN15_RS04410 (OHN15_04445) - 1006089..1007603 (+) 1515 WP_327123258.1 MFS transporter -
  OHN15_RS04415 (OHN15_04450) - 1007707..1008021 (+) 315 WP_327123259.1 DUF6332 family protein -
  OHN15_RS04420 (OHN15_04455) vraR 1007982..1008647 (-) 666 WP_327123260.1 response regulator transcription factor Regulator
  OHN15_RS04425 (OHN15_04460) - 1008644..1010029 (-) 1386 WP_406292083.1 sensor histidine kinase -
  OHN15_RS04430 (OHN15_04465) - 1010156..1010893 (-) 738 WP_327123261.1 TetR/AcrR family transcriptional regulator -
  OHN15_RS04435 (OHN15_04470) - 1011024..1011473 (+) 450 WP_327123262.1 nitroreductase family deazaflavin-dependent oxidoreductase -
  OHN15_RS04440 (OHN15_04475) - 1012053..1013267 (-) 1215 WP_371796735.1 geranylgeranyl reductase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23983.65 Da        Isoelectric Point: 4.7092

>NTDB_id=645291 OHN15_RS04420 WP_327123260.1 1007982..1008647(-) (vraR) [Streptomyces sp. NBC_00624]
MIRVLLADDQLLVRAGFRALLDAQPDIEVAGEAADGEEAVRLVRELRPDTVLMDIRMPHLDGLAATRTITGDADLNDVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVGGDALLSPGVTRRLIAEFAARSKEPAAATGLSELTERER
EVMTLVGIGLSNEEIARRLVVSPLTAKTHVSRTMVKLGARDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=645291 OHN15_RS04420 WP_327123260.1 1007982..1008647(-) (vraR) [Streptomyces sp. NBC_00624]
GTGATCCGCGTACTGCTCGCCGATGACCAACTGCTGGTCCGGGCCGGTTTCCGCGCCCTGCTGGACGCCCAGCCGGACAT
CGAGGTGGCGGGGGAGGCCGCCGACGGCGAGGAGGCCGTACGTCTGGTGCGCGAACTGCGGCCGGACACCGTGCTGATGG
ACATCCGGATGCCGCATCTCGACGGCCTCGCCGCCACCCGCACGATCACCGGGGATGCGGATCTCAACGACGTCAAGGTG
GTCATGCTCACCACCTTCGAGCTCGACGAGTACGTCTTCGAGGCGATCCGCTCCGGCGCCTCCGGTTTCCTGGTCAAGGA
CACCGAACCCGAGGAATTGCTGCGGGCGGTAAGGGCAGTGGTGGGCGGCGACGCGCTGCTCTCGCCCGGAGTGACCCGAC
GGCTGATCGCCGAGTTCGCGGCCCGCTCCAAGGAGCCTGCGGCCGCGACGGGACTGAGCGAACTCACCGAACGCGAAAGG
GAAGTGATGACGCTGGTCGGCATCGGCCTCTCCAACGAGGAAATCGCCCGCCGACTCGTCGTCAGCCCGCTCACCGCGAA
GACCCACGTCAGCCGCACCATGGTGAAGCTCGGTGCCCGCGACCGGGCCCAACTCGTCGTGCTCGCCTATGAGTCGGGAC
TCGTACGCCCCGGTTGGCTCGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(154-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.14

97.285

0.371
  degU Bacillus subtilis subsp. subtilis str. 168

35.556

100

0.362