Detailed information NTG0645223

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: OG961_RS21520
• Genome accession: NZ_CP107741
• Coordinates: 4761714..4762838 (+)
• Length: 374 a.a.
• NCBI ID: WP_266711290.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_00626
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4756714..4767838

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OG961_RS21505 (OG961_21530)	-	4757340..4758221 (+)	882	WP_327662853.1	hypothetical protein	-
OG961_RS21510 (OG961_21535)	-	4758252..4759964 (-)	1713	WP_327670762.1	BACON domain-containing protein	-
OG961_RS21515 (OG961_21540)	radA/sms	4760215..4761621 (+)	1407	WP_266711289.1	DNA repair protein RadA	Machinery gene
OG961_RS21520 (OG961_21545)	disA	4761714..4762838 (+)	1125	WP_266711290.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
OG961_RS21525 (OG961_21550)	-	4762915..4763748 (-)	834	WP_327670763.1	hypothetical protein	-
OG961_RS21530 (OG961_21555)	-	4763935..4764600 (+)	666	WP_327662850.1	phosphatase PAP2 family protein	-
OG961_RS21535 (OG961_21560)	-	4764679..4765362 (-)	684	WP_327662849.1	response regulator transcription factor	-
OG961_RS21540 (OG961_21565)	-	4765350..4766942 (-)	1593	WP_327670764.1	histidine kinase	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40051.83 Da
• Isoelectric Point: 4.9989

>NTDB_id=645223 OG961_RS21520 WP_266711290.1 4761714..4762838(+) (disA) [Streptomyces sp. NBC_00626]
MAANDRAATPGKSGGSSGADSLMRAALSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVVSSNLDKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGYTVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVARDYVPEPTAKRSRTVPEALVELDALSHAELLELPIVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=645223 OG961_RS21520 WP_266711290.1 4761714..4762838(+) (disA) [Streptomyces sp. NBC_00626]
GTGGCAGCCAATGACCGGGCGGCAACTCCCGGCAAGTCCGGCGGAAGCTCCGGTGCGGACAGTCTGATGCGCGCCGCGCT
GAGTGCCGTCGCGCCCGGAACCGCCCTGCGCGACGGCCTGGAGCGCATCCTCCGCGGCAACACCGGAGGACTCATCGTCC
TCGGCTCCGACAAGACGGTCGAGTCGATGTGCACGGGCGGCTTCATCCTCGACGTGGAGTTCACGGCCACGCGCCTGCGC
GAGCTGTGCAAACTCGACGGCGGCATCGTGGTCTCCTCGAACCTCGACAAGATCCTGCGGGCCGGCGTCCAGTTGGTGCC
GGACCCCACGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACGGCGGACCGGGTCTCCAAGCAGGTCGGCTACACCG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCGCTGTACGTGGACGGGCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGGGCCAACCAGGCCCTCGCGACCCTGGAGCGCTACAAGCTGCGCCTCGACGAGGTGGCGGGCACGCTCTC
CGCCCTGGAGATCGAGGACCTGGTCACGGTCCGGGACGTCTCGGCGGTCGCGCAGCGCCTGGAGATGGTGCGGCGCATCG
CCACGGAGATCGCCGAGTACGTCGTCGAGTTGGGCACGGACGGCCGGCTTCTGGCGCTGCAGCTCGACGAGTTGATCGCG
GGCGTCGAGCCGGAGCGCGAACTGGTCGCGCGGGACTACGTGCCCGAGCCCACCGCCAAGCGTTCCCGCACGGTCCCGGA
GGCGCTGGTCGAGCTGGACGCGCTCAGCCACGCGGAACTGCTCGAACTGCCGATAGTGGCACGGGCACTGGGCTACACCG
GCTCCCCCGAGGCACTCGACTCGGCGGTGTCCCCGCGCGGCTTCCGTCTCCTGGCCAAGGTGCCGCGCCTCCCTGGCGCC
ATCATCGACCGCCTCGTGGAGCACTTCGGCGGCCTGCAGAAGTTGCTGGCCGCGAGCGTGGACGACCTTCAGACGGTCGA
CGGGGTCGGAGAGGCGCGGGCGCGGAGCGTCCGGGAGGGCCTGTCGCGGTTGGCGGAGTCGTCGATCCTCGAGCGGTACG
TATAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.856	96.791	0.444