Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   SMSK321_RS08625 Genome accession   NZ_AEDT01000026
Coordinates   54752..55483 (+) Length   243 a.a.
NCBI ID   WP_000889953.1    Uniprot ID   E1LMF2
Organism   Streptococcus mitis SK321     
Function   export ComS (predicted from homology)   
Competence regulation

Genomic Context

Location: 49752..60483
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMSK321_RS08605 (SMSK321_1146) dnaK 50190..52013 (+) 1824 WP_000034667.1 molecular chaperone DnaK -
  SMSK321_RS08610 (SMSK321_1147) dnaJ 52562..53698 (+) 1137 WP_001066321.1 molecular chaperone DnaJ -
  SMSK321_RS08615 (SMSK321_1148) - 53977..54264 (-) 288 WP_000777748.1 hypothetical protein -
  SMSK321_RS08620 (SMSK321_1149) - 54274..54684 (-) 411 WP_001278320.1 HIT family protein -
  SMSK321_RS08625 (SMSK321_1150) pptA 54752..55483 (+) 732 WP_000889953.1 ABC transporter ATP-binding protein Regulator
  SMSK321_RS08630 (SMSK321_1151) pptB 55480..56529 (+) 1050 WP_000653758.1 ABC transporter permease Regulator
  SMSK321_RS08635 (SMSK321_1152) - 56592..56921 (-) 330 WP_000132580.1 hypothetical protein -
  SMSK321_RS08640 (SMSK321_1153) comE/blpR 57217..57954 (+) 738 WP_001219153.1 response regulator transcription factor Regulator
  SMSK321_RS08645 (SMSK321_1154) - 57968..59317 (+) 1350 WP_001017630.1 sensor histidine kinase -
  SMSK321_RS11840 - 59386..59742 (+) 357 WP_080550772.1 hypothetical protein -
  SMSK321_RS0102520 - 60032..60151 (+) 120 WP_000346299.1 PncF family bacteriocin immunity protein -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27084.55 Da        Isoelectric Point: 4.6934

>NTDB_id=64511 SMSK321_RS08625 WP_000889953.1 54752..55483(+) (pptA) [Streptococcus mitis SK321]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLTPYSGSININGLTLQEDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFDRVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAIADLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL

Nucleotide


Download         Length: 732 bp        

>NTDB_id=64511 SMSK321_RS08625 WP_000889953.1 54752..55483(+) (pptA) [Streptococcus mitis SK321]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTCCCTGTCTTGAAAGATGTGTCCTTTACTGTTGAAAGCGG
GCAGCTGGTCGGTCTGATTGGTCTCAATGGTGCTGGGAAATCAACGACTATTAATGAGATTATCGGTCTGTTGACACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACCCTGCAAGAAGATGCGACTAGTTACCGCAAGCAAATTGGCTACATTCCT
GAGACACCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTGGCTATGGCTTATGGTATTGAGCAGAA
AGTGGCTTTTGATCGAGTAGAACCCTTGTTAAAAATGTTCCGTCTGGACCAGAAATTAGACTGGTTTCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTCTTTATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGTTGGCTATTGCAGACTTGATTCAGCTTTTGGAAGTGGAAAAGCAAAAGGGCAAGTCCATTCTCAT
GAGTACCCACGTGCTGGATTCAGCGGAAAAGATGTGTGATGCTTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCTAAGG
GAAATCTCCTGCAACTGCGCGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACCAAAGAG
GAGGACCTATGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E1LMF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.614

99.177

0.72
  pptA Streptococcus thermophilus LMD-9

71.784

99.177

0.712

Multiple sequence alignment