Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   SMSK321_RS12050 Genome accession   NZ_AEDT01000012
Coordinates   48944..50746 (+) Length   600 a.a.
NCBI ID   WP_004234391.1    Uniprot ID   -
Organism   Streptococcus mitis SK321     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 43944..55746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMSK321_RS05060 (SMSK321_0440) rnr 44240..46594 (+) 2355 WP_000654874.1 ribonuclease R -
  SMSK321_RS05065 (SMSK321_0441) smpB 46557..47024 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  SMSK321_RS05070 (SMSK321_0442) tehB 47040..47900 (+) 861 WP_000413751.1 SAM-dependent methyltransferase TehB -
  SMSK321_RS12045 coiA 47972..48922 (+) 951 Protein_54 competence protein CoiA Machinery gene
  SMSK321_RS12050 (SMSK321_0443) pepF 48944..50746 (+) 1803 WP_004234391.1 oligoendopeptidase F Regulator
  SMSK321_RS05080 (SMSK321_0444) - 50748..51461 (+) 714 WP_029692162.1 O-methyltransferase -
  SMSK321_RS05085 (SMSK321_0445) prsA 51528..52466 (+) 939 WP_000727945.1 peptidylprolyl isomerase PrsA -
  SMSK321_RS05090 (SMSK321_0446) ftsW 52627..53850 (+) 1224 WP_004234396.1 cell division peptidoglycan polymerase FtsW -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69863.74 Da        Isoelectric Point: 4.5466

>NTDB_id=64501 SMSK321_RS12050 WP_004234391.1 48944..50746(+) (pepF) [Streptococcus mitis SK321]
MVLQRHEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADSLLEITEFSLEMERQMEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKNREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=64501 SMSK321_RS12050 WP_004234391.1 48944..50746(+) (pepF) [Streptococcus mitis SK321]
ATGGTATTACAAAGACATGAAATAAATGAAAAAGATACGTGGGATCTATCGACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCATTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGTCATCTCCTGGATAGTGCGGATAGTC
TACTCGAAATTACTGAATTTTCTCTTGAGATGGAACGCCAAATGGAGAAGCTTTACGTTTATGCTCATATGAAAAATGAC
CAGGACACACGTGAAGCCAAGTATCAAGAGTACTATGCCAAGGCCATGACTCTCTATAGCCAGCTAGACCAAGCCTTTTC
ATTCTATGAACCTGAATTTATGGAAATCAGTGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAGCCAAAATTGCAGGTTT
ATCAACACTATTTTGACAAGCTTTTGCAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTAGCTGGAGCT
GGGGAAATCTTTGGTTCGGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGTTCTTGACGA
TGATGGTAAGGAGGTTCAACTCTCTCATGGGACTTACACCCGTTTGATGGAGTCTAAAAATCGTGAGGTGCGTCGTGGTG
CCTATCAAGCTCTTTATGCGACTTATGAACAATTCCAACATACCTATGCCAAAACCTTGCAAACCAATGTTAAGGTCCAA
AACTACCGAGCAAAAGTTCGCAACTACAAGAGTGCTCGTCATGCAGCTCTTGCAGCAAATTTTGTCCCAGAGAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGTAAGCATTTGCCACTCTTGCATCGTTACCTTGAACTTCGTTCAAAAATCTTGGGAA
TTTCAGACCTCAAGATGTACGATGTCTACACACCACTTTCATCTGTTGAATACAGTTTTACCTACCAAGAAGCCTTGAAA
AAAGCAGAAGATGCCTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTTTAGCGAGCGTTGGATTGA
TGTTTATGAAAATCAAGGCAAGCGTTCAGGGGCCTACTCTGGTGGTTCTTACGATACAAATGCCTTTATGCTCCTTAACT
GGCAGGACAATCTAGACAATCTCTTTACTCTTGTCCATGAAACAGGTCATAGTATGCATTCAAGCTATACTCGTGAAACT
CAGCCTTATGTTTACGGGGATTACTCTATCTTCTTGGCTGAGATTGCCTCAACGACCAATGAAAATATCTTGACGGAAAA
ATTATTGGAAGAAGTGGAAGATGATGCAACGCGCTTTGCTATTCTCAATAACTTCCTAGACGGTTTCCGTGGAACAGTTT
TCCGCCAAACTCAATTTGCCGAGTTCGAACACGCAATCCATCAAGCAGACCAAAATGGAGAAGTCTTGACAAGTGATTTC
TTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGATAATCCTGAAATCCAATACGAGTG
GGCACGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACAGGCTTTGCAGCAGCTTCAGCTCTGGCTG
AAAAGATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATTGATTACCTCAAGGCAGGTAAGTCTGACTATCCACTT
AATGTTATGAGAAAAGCTGGCGTTGATATGGAGAAGGAAGACTATCTCAACGATGCTTTTGCAGTCTTCGAACGTCGTTT
GAATGAGTTTGAAGCTCTTGTTGAAAAATTGGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.282

99.333

0.668

Multiple sequence alignment