Detailed information    

experimental Experimentally validated

Overview

Name   coiA   Type   Machinery gene
Locus tag   SMSK321_RS12045 Genome accession   NZ_AEDT01000012
Coordinates   47972..48922 (+) Length   316 a.a.
NCBI ID   Protein_54    Uniprot ID   -
Organism   Streptococcus mitis SK321     
Function   homologous recombination   
Homologous recombination

Function

Upregulated in response to CSP as measured by RNA-seq.


Genomic Context

Location: 42972..53922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMSK321_RS05050 rpmG 43717..43866 (+) 150 WP_001809104.1 50S ribosomal protein L33 -
  SMSK321_RS05055 (SMSK321_0439) secG 43906..44139 (+) 234 WP_000282517.1 preprotein translocase subunit SecG -
  SMSK321_RS05060 (SMSK321_0440) rnr 44240..46594 (+) 2355 WP_000654874.1 ribonuclease R -
  SMSK321_RS05065 (SMSK321_0441) smpB 46557..47024 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  SMSK321_RS05070 (SMSK321_0442) tehB 47040..47900 (+) 861 WP_000413751.1 SAM-dependent methyltransferase TehB -
  SMSK321_RS12045 coiA 47972..48922 (+) 951 Protein_54 competence protein CoiA Machinery gene
  SMSK321_RS12050 (SMSK321_0443) pepF 48944..50746 (+) 1803 WP_004234391.1 oligoendopeptidase F Regulator
  SMSK321_RS05080 (SMSK321_0444) - 50748..51461 (+) 714 WP_029692162.1 O-methyltransferase -
  SMSK321_RS05085 (SMSK321_0445) prsA 51528..52466 (+) 939 WP_000727945.1 peptidylprolyl isomerase PrsA -
  SMSK321_RS05090 (SMSK321_0446) ftsW 52627..53850 (+) 1224 WP_004234396.1 cell division peptidoglycan polymerase FtsW -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: Da        Isoelectric Point:

>NTDB_id=523 SMSK321_RS12045 Protein_54 47972..48922(+) (coiA) [Streptococcus mitis SK321]
None

Nucleotide


Download         Length: 951 bp        

>NTDB_id=523 SMSK321_RS12045 Protein_54 47972..48922(+) (coiA) [Streptococcus mitis SK321]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGTCAGCTCCGTTTGCGTCAAGGGCCAAGTGTCCGGACCCATTTTGCCCACAAAACCTTAAAAGACTGTG
ATTTTTCCTCTGAAAATGAAAGTCCAGAACACCTAGAAAATAAAAAATCACTTTATCACTGGTTGAAAAAAGATGCAGAG
GTGCAATTAGAATACCCTCTTCCAGAGCTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTTTAGAGGTTCA
ATGTAGTCCCTTGCCTCAAAAAATTCTTAAGGAGCGTAGTGAGGGTTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGGGAAAAACTTTGGCTCAAGGATCGTTTGACTCGTCTGCAACAAGGTTTTCTATACTTCAGTCAAAACATGGGATTT
TATGTTTGGGAATTGGACAAGGAAAAACAGCTTTTAAGACTCAAATATCTCATCCACCAGGATCTCCGAGGTAAACTCCA
TTATCAAATCAAGGAATTTCCTTATGGACAAGATAGTCTACTGGAGATATTACGTTTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTCAGGACAAGGACATCTGTCGCTATATCCGACAACAACTCTATTATCAAAATCCCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGGGAAAATCTCCTAACTTATGGACTAAAAGAATTGTATCCACAAATAAGACC
ACTAGTAGGTAATTTTTGCCAAATTGAGCAAGATTTGACTCGCTATTATCAGTATTTTCAAACCTATTATCAACAAAATC
CTCAAAATGATTGGCAAAAGCTCTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value

References

[1] G Salvadori et al. (2018) High-resolution profiles of the Streptococcus mitis CSP signaling pathway reveal core and strain-specific regulated genes. BMC Genomics 19(1):453. [PMID: 29898666]