Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N4T39_RS09775 Genome accession   NZ_CP107720
Coordinates   2028142..2028798 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 2021CK-01361     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2023142..2033798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N4T39_RS09740 (N4T39_09740) dcyD 2023598..2024584 (+) 987 WP_032265403.1 D-cysteine desulfhydrase -
  N4T39_RS09745 (N4T39_09745) tcyL 2024599..2025267 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  N4T39_RS09750 (N4T39_09750) tcyN 2025264..2026016 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N4T39_RS09755 (N4T39_09755) - 2026246..2026578 (+) 333 Protein_1917 autoinducer binding domain-containing protein -
  N4T39_RS09760 (N4T39_09760) - 2026635..2027332 (+) 698 WP_103215986.1 IS1-like element IS1A family transposase -
  N4T39_RS09765 (N4T39_09765) yecF 2027459..2027683 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  N4T39_RS09770 (N4T39_09770) yecU 2027670..2027846 (-) 177 WP_000590347.1 protein YecU -
  N4T39_RS26625 - 2027929..2028000 (-) 72 Protein_1921 transcriptional regulator -
  N4T39_RS09775 (N4T39_09775) letA 2028142..2028798 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N4T39_RS09780 (N4T39_09780) uvrC 2028795..2030627 (+) 1833 WP_001283412.1 excinuclease ABC subunit UvrC Machinery gene
  N4T39_RS09785 (N4T39_09785) pgsA 2030684..2031232 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N4T39_RS09805 (N4T39_09805) yecA 2031882..2032547 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=644969 N4T39_RS09775 WP_000611335.1 2028142..2028798(+) (letA) [Escherichia coli strain 2021CK-01361]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=644969 N4T39_RS09775 WP_000611335.1 2028142..2028798(+) (letA) [Escherichia coli strain 2021CK-01361]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486