Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   KB225_RS00170 Genome accession   NZ_CP090575
Coordinates   42753..44102 (-) Length   449 a.a.
NCBI ID   WP_020368079.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain 11H     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 41103..50953 42753..44102 within 0


Gene organization within MGE regions


Location: 41103..50953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KB225_RS00165 (KB225_00165) ccrB 41103..42731 (-) 1629 WP_002495147.1 cassette chromosome recombinase CcrB Machinery gene
  KB225_RS00170 (KB225_00170) ccrA 42753..44102 (-) 1350 WP_020368079.1 cassette chromosome recombinase CcrA Machinery gene
  KB225_RS00175 (KB225_00175) cch1 44336..46129 (-) 1794 WP_020368078.1 cassette chromosome replicative helicase -
  KB225_RS00180 (KB225_00180) ssb 46129..46425 (-) 297 WP_000221967.1 cassette chromosome ssDNA-binding protein -
  KB225_RS00185 (KB225_00185) - 46597..48180 (+) 1584 WP_001551935.1 hypothetical protein -
  KB225_RS00190 (KB225_00190) - 48252..49184 (+) 933 WP_000364405.1 hypothetical protein -
  KB225_RS00195 (KB225_00195) - 49610..49987 (+) 378 WP_000687965.1 hypothetical protein -
  KB225_RS00200 (KB225_00200) - 50456..50953 (+) 498 WP_000051479.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52505.24 Da        Isoelectric Point: 9.8772

>NTDB_id=643578 KB225_RS00170 WP_020368079.1 42753..44102(-) (ccrA) [Staphylococcus epidermidis strain 11H]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVKNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDDTFINRQPYQVRNIIMNPNYCGRVINQYGQFDNMFPSIVSANV
YEQAQRLRSQKQTKQTPSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNLNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDHHIYAKIKNAIDKRLKRQRNTETHHTLTQEKLIEKLAQGIIDAETFRKQMQSLHQQPQRITSISEHQIQHTIQ
NIIQKRFTLNILYPYIETIHIAKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=643578 KB225_RS00170 WP_020368079.1 42753..44102(-) (ccrA) [Staphylococcus epidermidis strain 11H]
ATGAAACAAGTTATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACTTACCATGTTCATATCTTAAGCGTACATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCAGATAATATTGGAGAAC
AAGTCAAAAATGGCCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGCTACGACTATCAC
AACGGAACATTCATCATCAATCAAAATGAATCACCAACGGTGAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATGATACGTTCATCAATCGACAACCTTATCAAGTTCGTAATATTATCATGA
ACCCTAATTATTGTGGTCGTGTTATCAACCAATACGGTCAATTCGACAATATGTTCCCTTCTATTGTTTCAGCAAATGTA
TATGAACAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACACCTTCAGATAATCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACTTGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAAAAGTG
TGCCAAGACTTTTATCAAGACCACCATATCTACGCAAAAATTAAAAATGCGATTGACAAACGCTTAAAAAGACAACGAAA
CACAGAAACACATCACACACTGACTCAAGAAAAACTAATAGAAAAGTTAGCCCAAGGCATCATCGATGCAGAAACGTTCA
GAAAACAAATGCAATCATTACATCAACAACCGCAACGCATCACATCCATCAGTGAGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCTTATATTGAAACCATTCACATTGCGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCTCTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

92.205

100

0.922
  ccrA Staphylococcus aureus COL

75.278

100

0.753