Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   OF379_RS09290 Genome accession   NZ_CP107284
Coordinates   1970040..1970696 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain SW4848     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1965040..1975696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OF379_RS09260 (OF379_09260) dcyD 1965919..1966905 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  OF379_RS09265 (OF379_09265) tcyL 1966920..1967588 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  OF379_RS09270 (OF379_09270) tcyN 1967585..1968337 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  OF379_RS09275 (OF379_09275) sdiA 1968567..1969289 (+) 723 WP_001154287.1 transcriptional regulator SdiA -
  OF379_RS09280 (OF379_09280) yecF 1969357..1969581 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  OF379_RS09285 (OF379_09285) yecU 1969568..1969744 (-) 177 WP_000590347.1 protein YecU -
  OF379_RS25590 - 1969782..1969898 (-) 117 WP_001302039.1 hypothetical protein -
  OF379_RS09290 (OF379_09290) letA 1970040..1970696 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  OF379_RS09295 (OF379_09295) uvrC 1970693..1972525 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  OF379_RS09300 (OF379_09300) pgsA 1972582..1973130 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  OF379_RS09320 (OF379_09320) yecA 1973780..1974445 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=643432 OF379_RS09290 WP_000611335.1 1970040..1970696(+) (letA) [Escherichia coli strain SW4848]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=643432 OF379_RS09290 WP_000611335.1 1970040..1970696(+) (letA) [Escherichia coli strain SW4848]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486