Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   LZ178_RS00190 Genome accession   NZ_CP090375
Coordinates   49113..50738 (-) Length   541 a.a.
NCBI ID   WP_257241389.1    Uniprot ID   -
Organism   Staphylococcus aureus strain GD4SA108-1     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 49113..65931 49113..50738 within 0


Gene organization within MGE regions


Location: 49113..65931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LZ178_RS00190 (LZ178_00190) ccrB 49113..50738 (-) 1626 WP_257241389.1 recombinase family protein Machinery gene
  LZ178_RS00195 (LZ178_00195) ccrA 50758..52107 (-) 1350 WP_257241390.1 recombinase family protein Machinery gene
  LZ178_RS00200 (LZ178_00200) - 52299..52574 (-) 276 WP_053027474.1 hypothetical protein -
  LZ178_RS00205 (LZ178_00205) - 52643..54430 (-) 1788 WP_044466492.1 DUF927 domain-containing protein -
  LZ178_RS00210 (LZ178_00210) - 54556..55983 (-) 1428 WP_259489399.1 DUF6038 family protein -
  LZ178_RS00215 (LZ178_00215) - 56408..57082 (-) 675 WP_072291720.1 IS6-like element IS257 family transposase -
  LZ178_RS00220 (LZ178_00220) fexB 57732..59141 (-) 1410 WP_002415211.1 chloramphenicol/florfenicol efflux MFS transporter FexB -
  LZ178_RS00225 (LZ178_00225) - 59546..59713 (-) 168 Protein_42 recombinase family protein -
  LZ178_RS00230 (LZ178_00230) - 59770..60450 (-) 681 WP_002325565.1 IS6-like element IS1216 family transposase -
  LZ178_RS00235 (LZ178_00235) poxtA 60504..62132 (-) 1629 WP_002415638.1 ABC-F type ribosomal protection protein PoxtA -
  LZ178_RS00240 (LZ178_00240) - 63003..63677 (-) 675 WP_072291720.1 IS6-like element IS257 family transposase -
  LZ178_RS00245 (LZ178_00245) - 63718..63825 (-) 108 Protein_46 beta-lactam sensor/signal transducer MecR1 -
  LZ178_RS00250 (LZ178_00250) mecA 63922..65931 (+) 2010 WP_194376038.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 541 a.a.        Molecular weight: 62456.43 Da        Isoelectric Point: 9.7894

>NTDB_id=641789 LZ178_RS00190 WP_257241389.1 49113..50738(-) (ccrB) [Staphylococcus aureus strain GD4SA108-1]
MNEMKKKRIGAYIRVSTERQVEGYSIEGQITQIEQYCQFNGYELVDIYADRGISGKSMNRPELQRMLNDAKNGKLDCVMV
YKTNRLARNTSDLLTIVEELHRQNVEFFSLSERMEVKNSTGKLMLQILASFSEFERNTILENIYTGQRQRALEGYYQGNL
PLGYNNIPDNKKELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGNPFSISAVTYILSNPFYIGKIQFAKY
KDWNDKRRKGLNDKPVIAEGKHAPIIGKDLWDKVQARKKQVSQKPQVHGKGTNLLTGIIRCPQCGAPMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRAEVIEKYVMDQILEIVKSDKVLKQVVERVNQDSQIDMAALNHDIAYKQQQFDE
INTKLKNLVQTIEDNPDLTSALKPTIHQYETQLNDITNQMNQLKHQQNQEKPSYDTKQIAALLQRIFQNIESMDKSQIKA
LYLTVIDRIDIRKDENHKKQFYVTLKLNNEIIKQLFNNNNLDEVLLSTSSLFLPQTLYFQI

Nucleotide


Download         Length: 1626 bp        

>NTDB_id=641789 LZ178_RS00190 WP_257241389.1 49113..50738(-) (ccrB) [Staphylococcus aureus strain GD4SA108-1]
ATGAATGAAATGAAGAAGAAGAGAATCGGAGCGTACATTCGCGTGTCCACAGAGAGACAAGTAGAGGGTTATAGTATCGA
GGGACAAATTACACAAATAGAGCAATATTGCCAATTTAACGGCTATGAACTCGTTGATATATATGCAGATCGGGGTATAT
CAGGAAAATCTATGAACCGTCCTGAATTACAGCGCATGTTAAATGATGCTAAAAATGGAAAATTAGACTGTGTTATGGTT
TATAAAACAAATCGTTTGGCACGTAATACTTCCGATTTACTTACAATAGTCGAAGAACTTCATCGCCAAAATGTTGAATT
TTTTAGCTTATCTGAACGTATGGAAGTCAAAAATTCAACAGGCAAGTTAATGCTCCAGATACTTGCAAGTTTTTCCGAAT
TTGAAAGAAATACAATTTTAGAGAACATTTACACCGGACAACGTCAAAGAGCTTTAGAGGGCTATTATCAAGGCAATCTT
CCATTAGGATATAATAACATACCTGATAATAAAAAAGAATTAATGATTAATCAACATGAAGCTAACATCGTTAAATATAT
CTTTGAATCTTATGCCAAAGGTCATGGTTATCGTAAAATAGCCAATGCACTCAATCATAAAGGTTATGTCACTAAGAAAG
GTAATCCATTTAGTATTTCAGCTGTTACTTATATTCTCTCAAACCCATTCTATATTGGTAAAATTCAATTCGCGAAATAC
AAAGATTGGAATGATAAACGTCGTAAAGGCTTGAATGATAAGCCAGTAATCGCTGAAGGTAAGCACGCCCCTATTATTGG
CAAAGACTTATGGGATAAAGTACAAGCACGTAAAAAACAAGTTAGTCAAAAACCTCAAGTGCATGGAAAAGGAACCAATC
TATTAACAGGTATTATTCGCTGCCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGATGGT
ACCAAGAAGCGAATACGCTATTATTCTTGTAGTAACTTTCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGTGTTAG
AGCTGAGGTGATTGAGAAATACGTTATGGATCAAATACTTGAAATTGTCAAAAGCGATAAAGTTCTCAAACAAGTTGTCG
AACGTGTTAATCAAGATAGTCAAATTGATATGGCTGCACTTAACCATGATATCGCATATAAGCAACAACAATTTGATGAA
ATAAACACTAAACTAAAAAATCTAGTTCAAACCATCGAAGACAATCCAGACTTAACATCTGCACTCAAACCAACCATTCA
TCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAGCTCAAGCACCAACAAAATCAAGAGAAACCATCTT
ATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCCATGGATAAATCACAGATCAAAGCT
TTGTACCTAACGGTTATTGACCGTATTGATATTCGTAAAGATGAGAATCATAAAAAACAATTCTATGTCACTCTCAAGCT
CAATAATGAAATTATTAAACAACTTTTTAATAATAACAATCTAGACGAAGTGCTCCTCAGCACTTCGTCTTTGTTTTTGC
CTCAAACACTCTACTTTCAAATATAA

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(300-355)

Resolvase, N terminal domain (Resolvase)

(11-154)

Recombinase (Recombinase)

(179-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

79.889

100

0.8