Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ODQ18_RS19855 Genome accession   NZ_CP107039
Coordinates   3853962..3854597 (+) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain 11060     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3848962..3859597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ODQ18_RS19830 (ODQ18_19830) liaI 3850089..3850469 (+) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -
  ODQ18_RS19835 (ODQ18_19835) liaH 3850496..3851173 (+) 678 WP_003243047.1 stress responsive protein LiaH -
  ODQ18_RS19840 (ODQ18_19840) liaG 3851274..3852146 (+) 873 WP_003244420.1 DUF4097 domain-containing protein -
  ODQ18_RS19845 (ODQ18_19845) liaF 3852180..3852905 (+) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  ODQ18_RS19850 (ODQ18_19850) liaS 3852902..3853984 (+) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  ODQ18_RS19855 (ODQ18_19855) vraR 3853962..3854597 (+) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  ODQ18_RS19860 (ODQ18_19860) gerAC 3854605..3855726 (-) 1122 WP_003243203.1 spore germination receptor protein GerAC -
  ODQ18_RS19865 (ODQ18_19865) gerAB 3855723..3856820 (-) 1098 WP_128472263.1 spore germination receptor protein GerAB -
  ODQ18_RS19870 (ODQ18_19870) gerAA 3856789..3858237 (-) 1449 WP_003243555.1 spore germination receptor protein GerAA -
  ODQ18_RS19875 (ODQ18_19875) yvzF 3858355..3858540 (+) 186 WP_003244599.1 YvzF family protein -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=640338 ODQ18_RS19855 WP_003243201.1 3853962..3854597(+) (vraR) [Bacillus subtilis strain 11060]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=640338 ODQ18_RS19855 WP_003243201.1 3853962..3854597(+) (vraR) [Bacillus subtilis strain 11060]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408