Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | FH104_RS01375 | Genome accession | NZ_CP090014 |
| Coordinates | 283825..284409 (+) | Length | 194 a.a. |
| NCBI ID | WP_017175793.1 | Uniprot ID | A0A4V2KX31 |
| Organism | Staphylococcus hominis strain acrlk | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 285152..325877 | 283825..284409 | flank | 743 |
Gene organization within MGE regions
Location: 283825..325877
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FH104_RS01375 (FH104_01375) | comK/comK1 | 283825..284409 (+) | 585 | WP_017175793.1 | competence protein ComK | Regulator |
| FH104_RS01390 (FH104_01390) | - | 285152..285781 (-) | 630 | WP_242281803.1 | hypothetical protein | - |
| FH104_RS01395 (FH104_01395) | - | 286033..287514 (-) | 1482 | WP_242281804.1 | SH3 domain-containing protein | - |
| FH104_RS01400 (FH104_01400) | - | 287492..287977 (-) | 486 | WP_242281805.1 | phage holin | - |
| FH104_RS01405 (FH104_01405) | - | 288028..288519 (-) | 492 | WP_242281806.1 | holin family protein | - |
| FH104_RS01410 (FH104_01410) | - | 288576..288842 (-) | 267 | WP_070548292.1 | hypothetical protein | - |
| FH104_RS01415 (FH104_01415) | - | 288855..291140 (-) | 2286 | WP_242281807.1 | phage tail protein | - |
| FH104_RS01420 (FH104_01420) | - | 291149..292792 (-) | 1644 | WP_242281808.1 | polysaccharide deacetylase family protein | - |
| FH104_RS01425 (FH104_01425) | - | 292806..293645 (-) | 840 | WP_242281809.1 | phage tail domain-containing protein | - |
| FH104_RS01430 (FH104_01430) | - | 293649..300017 (-) | 6369 | WP_242281810.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| FH104_RS01435 (FH104_01435) | gpG | 300221..300754 (-) | 534 | WP_242281811.1 | phage tail assembly chaperone G | - |
| FH104_RS01440 (FH104_01440) | - | 300826..301416 (-) | 591 | WP_053020662.1 | major tail protein | - |
| FH104_RS01445 (FH104_01445) | - | 301423..301821 (-) | 399 | WP_242281812.1 | hypothetical protein | - |
| FH104_RS01450 (FH104_01450) | - | 301811..302236 (-) | 426 | WP_242281813.1 | HK97-gp10 family putative phage morphogenesis protein | - |
| FH104_RS01455 (FH104_01455) | - | 302236..302559 (-) | 324 | WP_242281814.1 | phage head closure protein | - |
| FH104_RS01460 (FH104_01460) | - | 302529..302852 (-) | 324 | WP_070436663.1 | head-tail connector protein | - |
| FH104_RS01465 (FH104_01465) | - | 302861..303037 (-) | 177 | WP_162837136.1 | hypothetical protein | - |
| FH104_RS01470 (FH104_01470) | - | 303050..304264 (-) | 1215 | WP_242281815.1 | phage major capsid protein | - |
| FH104_RS01475 (FH104_01475) | - | 304358..304942 (-) | 585 | WP_242281870.1 | HK97 family phage prohead protease | - |
| FH104_RS01480 (FH104_01480) | - | 304917..306155 (-) | 1239 | WP_242281816.1 | phage portal protein | - |
| FH104_RS01485 (FH104_01485) | - | 306171..306368 (-) | 198 | WP_242281817.1 | hypothetical protein | - |
| FH104_RS01490 (FH104_01490) | - | 306380..308089 (-) | 1710 | WP_242281818.1 | terminase large subunit | - |
| FH104_RS01495 (FH104_01495) | - | 308079..308546 (-) | 468 | WP_242281819.1 | phage terminase small subunit P27 family | - |
| FH104_RS01500 (FH104_01500) | - | 308690..308950 (-) | 261 | WP_176743909.1 | HNH endonuclease | - |
| FH104_RS01505 (FH104_01505) | - | 309247..309714 (-) | 468 | WP_242281820.1 | hypothetical protein | - |
| FH104_RS01510 (FH104_01510) | - | 309728..309910 (-) | 183 | WP_242281821.1 | DUF1514 family protein | - |
| FH104_RS01515 (FH104_01515) | - | 309923..310189 (-) | 267 | WP_242281822.1 | hypothetical protein | - |
| FH104_RS01520 (FH104_01520) | - | 310194..310688 (-) | 495 | WP_242281823.1 | hypothetical protein | - |
| FH104_RS01525 (FH104_01525) | - | 310688..310870 (-) | 183 | WP_242281824.1 | hypothetical protein | - |
| FH104_RS01530 (FH104_01530) | - | 310931..311185 (+) | 255 | WP_242281825.1 | hypothetical protein | - |
| FH104_RS01535 (FH104_01535) | - | 311252..311569 (-) | 318 | WP_242281826.1 | MazG-like family protein | - |
| FH104_RS01540 (FH104_01540) | - | 311562..311837 (-) | 276 | WP_242281827.1 | hypothetical protein | - |
| FH104_RS01545 (FH104_01545) | - | 311818..312021 (-) | 204 | WP_242281828.1 | hypothetical protein | - |
| FH104_RS01550 (FH104_01550) | - | 312012..312695 (-) | 684 | WP_242281829.1 | hypothetical protein | - |
| FH104_RS01555 (FH104_01555) | - | 312692..313453 (-) | 762 | WP_242281830.1 | ParB/RepB/Spo0J family partition protein | - |
| FH104_RS01560 (FH104_01560) | - | 313446..313913 (-) | 468 | WP_242281831.1 | DUF3310 domain-containing protein | - |
| FH104_RS01565 (FH104_01565) | - | 313918..314169 (-) | 252 | WP_242281832.1 | hypothetical protein | - |
| FH104_RS01570 (FH104_01570) | - | 314357..314551 (-) | 195 | WP_145452860.1 | hypothetical protein | - |
| FH104_RS01575 (FH104_01575) | - | 314554..314781 (-) | 228 | WP_107636309.1 | hypothetical protein | - |
| FH104_RS01580 (FH104_01580) | - | 314796..315029 (-) | 234 | WP_053022116.1 | hypothetical protein | - |
| FH104_RS01585 (FH104_01585) | - | 315029..315190 (-) | 162 | WP_172457911.1 | hypothetical protein | - |
| FH104_RS01590 (FH104_01590) | - | 315187..315975 (-) | 789 | WP_242281833.1 | ATP-binding protein | - |
| FH104_RS01595 (FH104_01595) | - | 315987..316808 (-) | 822 | WP_242281834.1 | DnaD domain protein | - |
| FH104_RS01600 (FH104_01600) | - | 316822..317499 (-) | 678 | WP_107636291.1 | putative HNHc nuclease | - |
| FH104_RS01605 (FH104_01605) | ssbA | 317511..317939 (-) | 429 | WP_242281835.1 | single-stranded DNA-binding protein | Machinery gene |
| FH104_RS01610 (FH104_01610) | - | 317957..318202 (-) | 246 | WP_242281836.1 | hypothetical protein | - |
| FH104_RS01615 (FH104_01615) | - | 318279..318452 (-) | 174 | WP_242281837.1 | hypothetical protein | - |
| FH104_RS01620 (FH104_01620) | - | 318483..318785 (-) | 303 | WP_242281838.1 | DUF771 domain-containing protein | - |
| FH104_RS01625 (FH104_01625) | - | 318849..319130 (+) | 282 | WP_242281839.1 | hypothetical protein | - |
| FH104_RS01630 (FH104_01630) | - | 319127..319390 (-) | 264 | WP_242281840.1 | hypothetical protein | - |
| FH104_RS01635 (FH104_01635) | - | 319442..319603 (-) | 162 | WP_242281841.1 | hypothetical protein | - |
| FH104_RS01640 (FH104_01640) | - | 319664..319903 (+) | 240 | WP_242281842.1 | hypothetical protein | - |
| FH104_RS01645 (FH104_01645) | - | 320079..320870 (-) | 792 | WP_242281843.1 | phage antirepressor | - |
| FH104_RS01650 (FH104_01650) | - | 320901..321125 (-) | 225 | WP_242281844.1 | DUF739 family protein | - |
| FH104_RS01655 (FH104_01655) | - | 321287..321667 (+) | 381 | WP_242281845.1 | helix-turn-helix domain-containing protein | - |
| FH104_RS01660 (FH104_01660) | - | 321798..322415 (-) | 618 | WP_242281846.1 | hypothetical protein | - |
| FH104_RS01665 (FH104_01665) | - | 322483..322947 (+) | 465 | WP_242281847.1 | ImmA/IrrE family metallo-endopeptidase | - |
| FH104_RS01670 (FH104_01670) | - | 322958..323491 (+) | 534 | WP_242281848.1 | hypothetical protein | - |
| FH104_RS01675 (FH104_01675) | - | 323517..324488 (+) | 972 | WP_242281849.1 | hypothetical protein | - |
| FH104_RS01680 (FH104_01680) | - | 324471..324647 (-) | 177 | WP_242281850.1 | hypothetical protein | - |
| FH104_RS01685 (FH104_01685) | - | 324816..325877 (+) | 1062 | WP_242281851.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 194 a.a. Molecular weight: 22941.26 Da Isoelectric Point: 9.5206
>NTDB_id=640199 FH104_RS01375 WP_017175793.1 283825..284409(+) (comK/comK1) [Staphylococcus hominis strain acrlk]
MTQFNKPPNTIYVIRKGDMVIRPTFDDHQQPNGSEILKFDTSREISPFKTQKIIERSCRFYGNNYLSKKAETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENIWINMHYISDIKPLKNRKSKIIFANQEALTLNVSFHSLWHQYSNSIFYYYMIDKQ
ARMKSNNPDMPIDYEKTSLNIFEALSHYSLLEDK
MTQFNKPPNTIYVIRKGDMVIRPTFDDHQQPNGSEILKFDTSREISPFKTQKIIERSCRFYGNNYLSKKAETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENIWINMHYISDIKPLKNRKSKIIFANQEALTLNVSFHSLWHQYSNSIFYYYMIDKQ
ARMKSNNPDMPIDYEKTSLNIFEALSHYSLLEDK
Nucleotide
Download Length: 585 bp
>NTDB_id=640199 FH104_RS01375 WP_017175793.1 283825..284409(+) (comK/comK1) [Staphylococcus hominis strain acrlk]
ATGACTCAGTTCAATAAACCTCCTAATACGATTTATGTCATACGTAAAGGTGATATGGTGATTAGACCTACATTTGACGA
TCATCAACAACCGAACGGCTCAGAAATCCTCAAATTCGATACCTCACGAGAAATAAGTCCTTTTAAAACTCAAAAAATTA
TTGAACGATCTTGTAGATTTTATGGCAATAACTACTTAAGCAAGAAAGCTGAAACTCAACGCATTGCTGGAATAACTAGT
AAACCTCCCATCCTTCTCACACCATTGTTTCCAACTTACTTTTTCCCAACACATTCAGACCGTTTAGAAGAAAATATATG
GATTAATATGCATTATATTTCTGATATTAAGCCATTAAAAAACAGAAAGAGTAAAATTATCTTTGCAAATCAAGAAGCAC
TAACATTAAATGTATCTTTTCATAGTTTATGGCATCAATATTCTAATTCTATTTTCTATTACTATATGATTGATAAACAA
GCAAGAATGAAATCTAATAATCCAGATATGCCAATCGATTATGAAAAAACATCTTTAAATATTTTTGAGGCACTTTCACA
CTATTCTTTATTAGAAGATAAATAG
ATGACTCAGTTCAATAAACCTCCTAATACGATTTATGTCATACGTAAAGGTGATATGGTGATTAGACCTACATTTGACGA
TCATCAACAACCGAACGGCTCAGAAATCCTCAAATTCGATACCTCACGAGAAATAAGTCCTTTTAAAACTCAAAAAATTA
TTGAACGATCTTGTAGATTTTATGGCAATAACTACTTAAGCAAGAAAGCTGAAACTCAACGCATTGCTGGAATAACTAGT
AAACCTCCCATCCTTCTCACACCATTGTTTCCAACTTACTTTTTCCCAACACATTCAGACCGTTTAGAAGAAAATATATG
GATTAATATGCATTATATTTCTGATATTAAGCCATTAAAAAACAGAAAGAGTAAAATTATCTTTGCAAATCAAGAAGCAC
TAACATTAAATGTATCTTTTCATAGTTTATGGCATCAATATTCTAATTCTATTTTCTATTACTATATGATTGATAAACAA
GCAAGAATGAAATCTAATAATCCAGATATGCCAATCGATTATGAAAAAACATCTTTAAATATTTTTGAGGCACTTTCACA
CTATTCTTTATTAGAAGATAAATAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
74.457 |
94.845 |
0.706 |
| comK/comK1 | Staphylococcus aureus N315 |
74.457 |
94.845 |
0.706 |