Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   LV497_RS06675 Genome accession   NZ_CP090007
Coordinates   1453793..1455112 (+) Length   439 a.a.
NCBI ID   WP_245084277.1    Uniprot ID   -
Organism   Streptococcus salivarius strain SALI-10     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1455093..1465359 1453793..1455112 flank -19


Gene organization within MGE regions


Location: 1453793..1465359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS06675 (LV497_06675) comFA/cflA 1453793..1455112 (+) 1320 WP_245084277.1 DEAD/DEAH box helicase Machinery gene
  LV497_RS06680 (LV497_06680) - 1455093..1455755 (+) 663 WP_002883740.1 ComF family protein -
  LV497_RS06685 (LV497_06685) raiA 1455834..1456382 (+) 549 WP_002883786.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  LV497_RS06740 (LV497_06740) - 1462303..1463235 (+) 933 WP_022495991.1 manganese-dependent inorganic pyrophosphatase -
  LV497_RS06745 (LV497_06745) - 1463290..1463949 (+) 660 WP_245084280.1 DUF1803 domain-containing protein -
  LV497_RS06750 (LV497_06750) - 1463979..1464512 (-) 534 WP_245084283.1 DUF402 domain-containing protein -
  LV497_RS06755 (LV497_06755) recX 1464583..1465359 (-) 777 WP_245084286.1 recombination regulator RecX -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50751.75 Da        Isoelectric Point: 8.8671

>NTDB_id=640140 LV497_RS06675 WP_245084277.1 1453793..1455112(+) (comFA/cflA) [Streptococcus salivarius strain SALI-10]
MVPKEYYGRLFTKEQLPVDYHSEAFTLESMIKVDKQLRCKRCYSQIEENWQLPEGQYYCRACIVFGRNQEGNELYYFPSK
TSEIEFPVLKWLGELTPYQAEVSEKLLETYQKQKDSLVHAVTGAGKTEMIYKIVAYVLESKGNVAIASPRVDVCRELFLR
MQRDFTCSISLLHAESEPYDGSPLVIATTHQLLKFYQNFDLVIVDEVDAFPFVGNVMLNHAVEQAKKETGRYIYLTATST
LSLEEQVRLGFLEKHHLARRFHGNPLVLPKFFWQGRLQKSLMRGKLPRPLVYQIKKQRKSKFPLLIFFPNIAIGEKFTSI
LQKYLPDEKMAFVSSKSEERSATVEQFREKELSILVTTTILERGVTFPQVDVFVCMANHHLYTSSSLIQIGGRVGRSPDR
PTGMLYFFHEGLSKSMLRCREEIKVMNKKGGFNNEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=640140 LV497_RS06675 WP_245084277.1 1453793..1455112(+) (comFA/cflA) [Streptococcus salivarius strain SALI-10]
ATGGTACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTGCCAGTGGACTATCACTCAGAGGCTTTTACATT
GGAAAGCATGATAAAGGTCGATAAACAACTTAGATGTAAAAGATGTTACAGTCAGATAGAAGAAAATTGGCAATTACCGG
AAGGTCAGTATTATTGCAGAGCATGTATTGTCTTTGGTAGAAATCAAGAAGGAAATGAACTCTATTATTTTCCTTCAAAA
ACATCTGAAATTGAATTTCCTGTTTTGAAGTGGTTGGGGGAACTGACTCCCTATCAAGCTGAGGTCTCAGAGAAGCTTTT
AGAAACATATCAAAAACAGAAAGACAGCCTCGTACATGCTGTGACTGGTGCTGGGAAGACCGAGATGATTTATAAAATCG
TTGCCTATGTTCTTGAAAGTAAAGGTAATGTAGCTATCGCAAGTCCTCGGGTTGATGTTTGTCGAGAGTTATTTCTTCGT
ATGCAGAGGGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGAGAGTGAACCATATGATGGTAGTCCGCTTGTAATAGC
TACCACCCATCAACTACTAAAGTTTTACCAGAACTTTGACCTAGTTATCGTTGATGAGGTTGATGCATTCCCTTTTGTAG
GAAATGTCATGTTAAATCATGCTGTGGAGCAGGCAAAGAAGGAAACCGGTCGCTATATTTATTTAACAGCGACTTCTACA
TTATCTTTAGAGGAGCAAGTGCGACTTGGATTTTTAGAAAAGCATCACCTTGCTAGACGTTTCCATGGAAATCCTTTAGT
ACTTCCCAAATTCTTTTGGCAGGGAAGACTACAAAAATCTCTAATGAGAGGCAAGCTTCCAAGACCTCTTGTTTATCAGA
TTAAAAAGCAACGTAAATCCAAATTCCCTCTATTAATCTTTTTTCCAAATATAGCGATAGGTGAAAAGTTTACTAGCATT
CTGCAAAAATATCTTCCAGACGAAAAAATGGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAGCTACCGTAGAGCAGTT
CCGGGAAAAAGAGTTATCCATCTTAGTGACAACAACTATCCTTGAACGTGGGGTAACCTTTCCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATACACTAGTTCGAGTCTTATTCAGATAGGAGGTCGAGTTGGAAGATCCCCAGATAGA
CCGACGGGAATGCTTTATTTCTTTCATGAAGGACTATCCAAATCAATGCTTCGTTGTCGAGAAGAAATAAAGGTTATGAA
TAAAAAAGGAGGATTTAACAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-170)

Helicase conserved C-terminal domain (Helicase_C)

(290-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae D39

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae R6

56.381

98.178

0.554
  comFA/cflA Streptococcus pneumoniae TIGR4

56.381

98.178

0.554
  comFA/cflA Streptococcus mitis NCTC 12261

55.53

98.861

0.549
  comFA/cflA Streptococcus mitis SK321

54.988

98.178

0.54
  comFA Lactococcus lactis subsp. cremoris KW2

45.952

95.672

0.44
  comFA Latilactobacillus sakei subsp. sakei 23K

37.844

99.317

0.376