Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ODS73_RS03345 Genome accession   NZ_CP107038
Coordinates   629318..631162 (+) Length   614 a.a.
NCBI ID   WP_001061135.1    Uniprot ID   C1CQA2
Organism   Streptococcus pneumoniae strain BM6001     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 624318..636162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ODS73_RS03325 (ODS73_03325) - 625150..625929 (+) 780 WP_000290020.1 alpha/beta hydrolase family protein -
  ODS73_RS03330 (ODS73_03330) murM 626041..627261 (+) 1221 WP_000286557.1 peptidoglycan bridge formation alanyltransferase MurM -
  ODS73_RS03335 (ODS73_03335) murN 627266..628498 (+) 1233 WP_001229509.1 peptidoglycan bridge formation alanyltransferase MurN -
  ODS73_RS03340 (ODS73_03340) - 628577..629278 (+) 702 WP_001267415.1 M57 family metalloprotease -
  ODS73_RS03345 (ODS73_03345) uvrC 629318..631162 (+) 1845 WP_001061135.1 excinuclease ABC subunit UvrC Machinery gene
  ODS73_RS03350 (ODS73_03350) - 631152..631985 (+) 834 WP_025169383.1 metallophosphoesterase -
  ODS73_RS03355 (ODS73_03355) - 632167..632967 (-) 801 WP_000714632.1 amino acid ABC transporter substrate-binding protein -
  ODS73_RS03360 (ODS73_03360) - 633138..633743 (+) 606 WP_000670172.1 nitroreductase family protein -
  ODS73_RS03365 (ODS73_03365) pepV 633756..635156 (+) 1401 WP_000560280.1 dipeptidase PepV -
  ODS73_RS03370 (ODS73_03370) - 635210..635788 (+) 579 WP_000078149.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70377.00 Da        Isoelectric Point: 9.3868

>NTDB_id=640099 ODS73_RS03345 WP_001061135.1 629318..631162(+) (uvrC) [Streptococcus pneumoniae strain BM6001]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDSKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNKP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=640099 ODS73_RS03345 WP_001061135.1 629318..631162(+) (uvrC) [Streptococcus pneumoniae strain BM6001]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTTCATCAAAATCACCAATGA
GCGCTATCCACGCTTGATTATCACTCGTCAGGTCAAAAAGGACGGAGGTCTTTATTTTGGACCTTATCCCGATGTGGGGG
CAGCCAATGAAATCAAGCGGTTGCTGGATCGGATATTCCCTTTTCGTAAGTGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGCCAGTGTATGGCTCACACCATCTGTAAGAAGGATGAGGCTTATTTCAAGTCTATGGCCCAGGAGGT
TTCTGATTTTCTGAAAGGGCAGGATAACAAAATCATTGATGAGCTAAAGGGCAAAATGGCAGCGGCAGCCCAGACTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTTCGTCAGGG
CAAGCTCATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTCTTGACCTATGTGGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAGGCTGTCAAGGCCTTG
GTGGATTCCAAGATTCTTAAGCCTCAACGTGGAGAGAAAAAGCAGCTGGTCAATTTAGCTATAAAAAATGCCCGTGTTAG
CCTAGAGCAGAAGTTCAACCTGCTAGAGAAATCTGTCGAGAAGACCCAAGGAGCTATTGAAAATCTAGGACGCTTGCTTC
AAATCCCAACCCCAGTTCGCATCGAGTCCTTCGATAACTCCAACATCATGGGAACTAGTCCTGTTTCAGCCATGGTGGTC
TTTGTCAACGGCAAGCCTAGTAAGAAGGATTACCGTAAGTATAAAATCAAGACCGTAGTCGGGCCAGACGACTATGCCAG
TATGCGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATTGCTAAGCAAGTCATCCAAGAAGAACTGGGCTTGGATATTCCAATTGCAGGTCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTGGAAGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCCATCACCTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTTATGAAGCATTTCAAGTCTTTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGGGTACCTAGAGTCGTTGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATAAAC
CATAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(197-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CQA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

99.023

100

0.99
  uvrC Streptococcus pneumoniae R6

98.534

100

0.985
  uvrC Streptococcus pneumoniae D39

98.534

100

0.985