Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ODS73_RS02370 Genome accession   NZ_CP107038
Coordinates   433651..434283 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain BM6001     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 428651..439283
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ODS73_RS02345 (ODS73_02345) mvaD 428928..429881 (+) 954 WP_000373461.1 diphosphomevalonate decarboxylase -
  ODS73_RS02350 (ODS73_02350) - 429868..430875 (+) 1008 WP_044727650.1 phosphomevalonate kinase -
  ODS73_RS02355 (ODS73_02355) fni 430859..431869 (+) 1011 WP_044727651.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ODS73_RS02360 (ODS73_02360) liaF 431947..432645 (+) 699 WP_044727652.1 cell wall-active antibiotics response protein LiaF -
  ODS73_RS02365 (ODS73_02365) - 432642..433637 (+) 996 WP_044727653.1 sensor histidine kinase -
  ODS73_RS02370 (ODS73_02370) vraR 433651..434283 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  ODS73_RS02380 (ODS73_02380) - 434347..435044 (+) 698 Protein_469 DNA alkylation repair protein -
  ODS73_RS02385 (ODS73_02385) - 435194..435433 (+) 240 WP_000754501.1 hypothetical protein -
  ODS73_RS02390 (ODS73_02390) cbpG 435514..436104 (+) 591 Protein_471 choline-binding protein CbpG -
  ODS73_RS02395 (ODS73_02395) - 436459..436797 (+) 339 WP_001812733.1 tyrosine-type recombinase/integrase -
  ODS73_RS02400 (ODS73_02400) tig 436958..438241 (+) 1284 WP_138009661.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=640088 ODS73_RS02370 WP_000698434.1 433651..434283(+) (vraR) [Streptococcus pneumoniae strain BM6001]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=640088 ODS73_RS02370 WP_000698434.1 433651..434283(+) (vraR) [Streptococcus pneumoniae strain BM6001]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGACGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41