Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LXA49_RS02130 Genome accession   NZ_CP089949
Coordinates   397358..398047 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SN75752     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 392358..403047
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA49_RS02105 (LXA49_02100) gpsB 392467..392796 (+) 330 WP_000146522.1 cell division regulator GpsB -
  LXA49_RS02115 (LXA49_02110) - 393282..394439 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  LXA49_RS02120 (LXA49_02115) mapZ 394452..395846 (+) 1395 WP_000039270.1 mid-cell-anchored protein MapZ -
  LXA49_RS02125 (LXA49_02120) gndA 395922..397346 (+) 1425 WP_000158794.1 NADP-dependent phosphogluconate dehydrogenase -
  LXA49_RS02130 (LXA49_02125) covR 397358..398047 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  LXA49_RS02135 (LXA49_02130) cbpC 398145..399164 (+) 1020 WP_000698033.1 choline-binding protein CbpC -
  LXA49_RS02140 (LXA49_02135) - 399282..400514 (-) 1233 WP_000765676.1 MFS transporter -
  LXA49_RS02145 (LXA49_02140) - 400673..401143 (-) 471 WP_001810352.1 lanthionine synthetase LanC family protein -
  LXA49_RS02150 (LXA49_02145) - 401043..401432 (-) 390 WP_013315042.1 lanthionine synthetase LanC family protein -
  LXA49_RS11100 - 402044..402373 (+) 330 WP_000196972.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=639394 LXA49_RS02130 WP_000518011.1 397358..398047(+) (covR) [Streptococcus pneumoniae strain SN75752]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=639394 LXA49_RS02130 WP_000518011.1 397358..398047(+) (covR) [Streptococcus pneumoniae strain SN75752]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467