Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   OEG89_RS05530 Genome accession   NZ_CP106929
Coordinates   1094183..1094839 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MFDS1001074     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1089183..1099839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OEG89_RS05500 (OEG89_05500) - 1090313..1091053 (+) 741 WP_095138828.1 hypothetical protein -
  OEG89_RS05520 (OEG89_05520) pgsA 1091749..1092297 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  OEG89_RS05525 (OEG89_05525) uvrC 1092354..1094186 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  OEG89_RS05530 (OEG89_05530) letA 1094183..1094839 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  OEG89_RS24320 - 1094981..1095052 (+) 72 Protein_1090 transcriptional regulator -
  OEG89_RS05535 (OEG89_05535) yecU 1095135..1095311 (+) 177 WP_000590347.1 protein YecU -
  OEG89_RS05540 (OEG89_05540) yecF 1095298..1095522 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  OEG89_RS05545 (OEG89_05545) sdiA 1095589..1096311 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  OEG89_RS05550 (OEG89_05550) tcyN 1096541..1097293 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  OEG89_RS05555 (OEG89_05555) tcyL 1097290..1097958 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  OEG89_RS05560 (OEG89_05560) dcyD 1097973..1098959 (-) 987 WP_001128233.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=638762 OEG89_RS05530 WP_000611335.1 1094183..1094839(-) (letA) [Escherichia coli strain MFDS1001074]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=638762 OEG89_RS05530 WP_000611335.1 1094183..1094839(-) (letA) [Escherichia coli strain MFDS1001074]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486