Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SLV14_RS14375 Genome accession   NZ_CP106840
Coordinates   3376378..3377019 (+) Length   213 a.a.
NCBI ID   WP_263269532.1    Uniprot ID   -
Organism   Streptomyces sp. Je 1-4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3371378..3382019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SLV14_RS14360 (SLV14_002879) - 3373303..3374205 (+) 903 WP_263269529.1 phosphorothioated DNA-binding restriction endonuclease -
  SLV14_RS14365 (SLV14_002880) - 3374247..3374801 (-) 555 WP_263269530.1 hypothetical protein -
  SLV14_RS14370 (SLV14_002881) - 3375053..3376381 (+) 1329 WP_263269531.1 sensor histidine kinase -
  SLV14_RS14375 (SLV14_002882) vraR 3376378..3377019 (+) 642 WP_263269532.1 response regulator Regulator
  SLV14_RS14380 (SLV14_002883) - 3377051..3377620 (-) 570 WP_208681251.1 class I SAM-dependent methyltransferase -
  SLV14_RS14385 (SLV14_002884) - 3377670..3378518 (+) 849 WP_263269533.1 AraC family transcriptional regulator -
  SLV14_RS14390 (SLV14_002885) - 3378585..3379793 (-) 1209 WP_263273142.1 DUF2786 domain-containing protein -
  SLV14_RS14395 (SLV14_002886) - 3379945..3380904 (-) 960 WP_263269534.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 22434.85 Da        Isoelectric Point: 5.3485

>NTDB_id=638474 SLV14_RS14375 WP_263269532.1 3376378..3377019(+) (vraR) [Streptomyces sp. Je 1-4]
MTDVENAAAVRVLLADDHPVVREGLCAMLESDPGIEVVGQAGSGEEAAALTERLAPDLVLLDLRMGAMDGVAATGHILRR
SPHTKVVIVTTYEDDSDILRAVEAGAAGYLLKGSSRAELIDAVHGAARGATVLTPSLAPKLFRARAVEAPLLSGRECEVL
RLVSQGLTNAEIGRQLFIGEATVKTHLLRAFKKLEVSDRTAAVITALERGLLA

Nucleotide


Download         Length: 642 bp        

>NTDB_id=638474 SLV14_RS14375 WP_263269532.1 3376378..3377019(+) (vraR) [Streptomyces sp. Je 1-4]
ATGACGGACGTGGAGAACGCGGCGGCGGTGCGGGTGCTGCTCGCGGACGATCATCCCGTCGTCCGCGAGGGCCTGTGCGC
CATGCTCGAATCCGACCCGGGCATCGAGGTCGTGGGGCAGGCGGGCTCCGGTGAGGAGGCCGCGGCGCTGACGGAACGGC
TGGCGCCGGACCTCGTACTGCTCGATCTGCGGATGGGGGCGATGGACGGGGTCGCCGCCACCGGACACATCCTGCGGCGG
TCGCCACACACCAAGGTCGTCATCGTCACCACCTACGAGGACGACTCCGACATCCTGCGCGCCGTGGAGGCGGGCGCGGC
CGGCTATCTCCTCAAGGGCAGTTCCCGGGCCGAGCTGATCGACGCCGTGCACGGTGCGGCGCGGGGGGCGACCGTGCTGA
CGCCTTCGCTGGCCCCCAAGCTGTTCCGGGCGCGGGCGGTGGAGGCGCCGCTGCTGTCCGGCCGGGAGTGCGAGGTGCTG
CGGCTGGTCAGCCAGGGCCTGACCAATGCCGAGATCGGCCGGCAGCTGTTCATCGGTGAGGCGACGGTCAAGACCCATCT
CCTGCGTGCGTTCAAGAAGCTGGAGGTGTCGGACCGGACCGCGGCCGTGATCACGGCGCTGGAGCGCGGCTTGCTGGCGT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(12-123)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.262

96.714

0.399
  degU Bacillus subtilis subsp. subtilis str. 168

36.323

100

0.38