Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   LU294_RS20340 Genome accession   NZ_CP089743
Coordinates   3914407..3915090 (-) Length   227 a.a.
NCBI ID   WP_000350710.1    Uniprot ID   Q81TR3
Organism   Bacillus paranthracis strain SHOU-BC01     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3909407..3920090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LU294_RS20325 (LU294_20325) pepF 3909588..3911414 (-) 1827 WP_000003390.1 oligoendopeptidase F Regulator
  LU294_RS20330 (LU294_20330) - 3911465..3912709 (-) 1245 WP_000612277.1 competence protein CoiA -
  LU294_RS20335 (LU294_20335) - 3912790..3914334 (-) 1545 WP_000799204.1 cardiolipin synthase -
  LU294_RS20340 (LU294_20340) mecA 3914407..3915090 (-) 684 WP_000350710.1 adaptor protein MecA Regulator
  LU294_RS20345 (LU294_20345) - 3915430..3916104 (+) 675 WP_000362603.1 TerC family protein -
  LU294_RS20350 (LU294_20350) spx 3916154..3916549 (-) 396 WP_000258267.1 transcriptional regulator Spx -
  LU294_RS20355 (LU294_20355) - 3917142..3917345 (+) 204 WP_000559978.1 hypothetical protein -
  LU294_RS20360 (LU294_20360) - 3917373..3919019 (-) 1647 WP_136444318.1 peptide ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 26966.00 Da        Isoelectric Point: 3.9822

>NTDB_id=638450 LU294_RS20340 WP_000350710.1 3914407..3915090(-) (mecA) [Bacillus paranthracis strain SHOU-BC01]
MDIERINDHTMKFFITYIDIEDRGFNREEIWYDRERSEELFWEMMDEARDHDDFFIDGPLWIQVQAVDKGIEVLVTKAEL
SKDGQKLELPIGVDKIIDIPLDEGIESLFQQELVEEVEEQAGTNFNEDGTFGFLIKFNDFEDVISLSHRLIFEDIKDELY
SFEDRYYVYVEFDEVLHDEEEIDRILSIVLEYGEESTLTIHRVSEYGKQIVKEHALETIRNNFPAKT

Nucleotide


Download         Length: 684 bp        

>NTDB_id=638450 LU294_RS20340 WP_000350710.1 3914407..3915090(-) (mecA) [Bacillus paranthracis strain SHOU-BC01]
TTGGATATTGAAAGAATTAATGATCATACGATGAAATTTTTTATTACGTACATTGATATAGAGGACAGAGGCTTTAATCG
TGAGGAAATTTGGTATGACCGCGAAAGAAGCGAAGAGCTCTTTTGGGAAATGATGGACGAAGCTCGTGATCATGACGATT
TCTTTATTGATGGGCCGTTATGGATTCAAGTGCAAGCAGTCGATAAAGGGATTGAAGTACTTGTAACGAAAGCAGAACTT
TCAAAGGATGGACAAAAGCTAGAACTACCAATAGGTGTAGATAAAATTATAGACATTCCTCTAGATGAAGGTATTGAATC
ATTATTCCAGCAAGAATTAGTGGAAGAGGTAGAGGAACAAGCAGGTACAAACTTTAACGAAGATGGTACGTTTGGCTTTT
TAATTAAGTTTAATGATTTTGAAGATGTCATTTCATTAAGTCATCGTCTTATCTTTGAAGATATAAAAGATGAGCTGTAT
TCATTTGAGGACCGCTATTATGTATATGTGGAATTCGATGAAGTGCTACATGATGAAGAAGAAATTGATCGCATTTTAAG
CATTGTTTTAGAATACGGGGAAGAATCAACTTTAACAATTCATCGTGTAAGTGAGTATGGGAAACAAATTGTGAAAGAGC
ATGCGCTTGAAACAATTCGCAATAATTTTCCTGCTAAAACGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81TR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

56.14

100

0.564