Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   U064_RS00200 Genome accession   NC_022911
Coordinates   37508..38251 (+) Length   247 a.a.
NCBI ID   WP_023591494.1    Uniprot ID   -
Organism   Helicobacter pylori BM012S     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32508..43251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U064_RS00175 (U064_0035) panD 34675..35028 (+) 354 WP_023591491.1 aspartate 1-decarboxylase -
  U064_RS00180 (U064_0036) - 35031..35324 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  U064_RS00185 (U064_0037) - 35324..36319 (+) 996 WP_041200974.1 PDZ domain-containing protein -
  U064_RS00190 (U064_0038) comB6 36327..37382 (+) 1056 WP_023591493.1 P-type conjugative transfer protein TrbL Machinery gene
  U064_RS00195 (U064_0039) comB7 37398..37511 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  U064_RS00200 (U064_0040) comB8 37508..38251 (+) 744 WP_023591494.1 type IV secretion system protein Machinery gene
  U064_RS00205 (U064_0041) comB9 38251..39237 (+) 987 WP_041200975.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  U064_RS00210 (U064_0042) comB10 39230..40366 (+) 1137 WP_023591496.1 DNA type IV secretion system protein ComB10 Machinery gene
  U064_RS00215 (U064_0043) - 40437..41849 (+) 1413 WP_023591497.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  U064_RS00220 (U064_0044) gmd 41879..43024 (+) 1146 WP_023591498.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28639.85 Da        Isoelectric Point: 8.9546

>NTDB_id=63840 U064_RS00200 WP_023591494.1 37508..38251(+) (comB8) [Helicobacter pylori BM012S]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=63840 U064_RS00200 WP_023591494.1 37508..38251(+) (comB8) [Helicobacter pylori BM012S]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCAGTGAGTGATTTGGACATGCAAAGCGTGTTTCGGTTGGAAAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGAGCGTATGTGTTGAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAGGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCACAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCCGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTCACCCGCTACAGCATCACTGAAATT
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.976

100

0.98

Multiple sequence alignment