Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUY95_RS02580 Genome accession   NZ_CP089506
Coordinates   458944..459630 (+) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain 0.0066_IIV_ST239     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 453944..464630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY95_RS02545 yqeH 454471..455571 (+) 1101 WP_001280134.1 ribosome biogenesis GTPase YqeH -
  LUY95_RS02550 aroE 455585..456391 (+) 807 WP_000666750.1 shikimate dehydrogenase -
  LUY95_RS02555 yhbY 456395..456685 (+) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  LUY95_RS02560 nadD 456688..457257 (+) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUY95_RS02565 yqeK 457247..457831 (+) 585 WP_001019327.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUY95_RS02570 rsfS 457832..458185 (+) 354 WP_001088020.1 ribosome silencing factor -
  LUY95_RS02575 - 458188..458904 (+) 717 WP_000084835.1 class I SAM-dependent methyltransferase -
  LUY95_RS02580 comEA 458944..459630 (+) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  LUY95_RS02585 - 459722..460183 (+) 462 WP_000439692.1 ComE operon protein 2 -
  LUY95_RS02590 comEC 460188..462389 (+) 2202 WP_000967506.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LUY95_RS02595 holA 462446..463420 (+) 975 WP_001282570.1 DNA polymerase III subunit delta -
  LUY95_RS02600 rpsT 463465..463716 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=637766 LUY95_RS02580 WP_001794049.1 458944..459630(+) (comEA) [Staphylococcus aureus strain 0.0066_IIV_ST239]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637766 LUY95_RS02580 WP_001794049.1 458944..459630(+) (comEA) [Staphylococcus aureus strain 0.0066_IIV_ST239]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952