Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUZ01_RS02145 Genome accession   NZ_CP089504
Coordinates   400120..400806 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 3581_IA_ST247     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 395120..405806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ01_RS02110 yqeH 395647..396747 (+) 1101 WP_023487011.1 ribosome biogenesis GTPase YqeH -
  LUZ01_RS02115 aroE 396761..397567 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  LUZ01_RS02120 yhbY 397571..397861 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  LUZ01_RS02125 nadD 397864..398433 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUZ01_RS02130 yqeK 398423..399007 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUZ01_RS02135 rsfS 399008..399361 (+) 354 WP_001088022.1 ribosome silencing factor -
  LUZ01_RS02140 - 399364..400080 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  LUZ01_RS02145 comEA 400120..400806 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  LUZ01_RS02150 - 400898..401359 (+) 462 WP_000439693.1 ComE operon protein 2 -
  LUZ01_RS02155 - 401364..403565 (+) 2202 Protein_390 DNA internalization-related competence protein ComEC/Rec2 -
  LUZ01_RS02160 holA 403622..404596 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  LUZ01_RS02165 rpsT 404641..404892 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=637725 LUZ01_RS02145 WP_001792568.1 400120..400806(+) (comEA) [Staphylococcus aureus strain 3581_IA_ST247]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637725 LUZ01_RS02145 WP_001792568.1 400120..400806(+) (comEA) [Staphylococcus aureus strain 3581_IA_ST247]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969