Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUZ00_RS08935 Genome accession   NZ_CP089498
Coordinates   1784673..1785359 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain M03/0073_III_ST239     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1779673..1790359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ00_RS08915 rpsT 1780587..1780838 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  LUZ00_RS08920 holA 1780883..1781857 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  LUZ00_RS08925 comEC 1781914..1784115 (-) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LUZ00_RS08930 - 1784120..1784581 (-) 462 WP_000439693.1 ComE operon protein 2 -
  LUZ00_RS08935 comEA 1784673..1785359 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  LUZ00_RS08940 - 1785399..1786115 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  LUZ00_RS08945 rsfS 1786118..1786471 (-) 354 WP_001088022.1 ribosome silencing factor -
  LUZ00_RS08950 yqeK 1786472..1787056 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUZ00_RS08955 nadD 1787046..1787615 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUZ00_RS08960 yhbY 1787618..1787908 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  LUZ00_RS08965 aroE 1787912..1788718 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  LUZ00_RS08970 yqeH 1788732..1789832 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=637614 LUZ00_RS08935 WP_001792568.1 1784673..1785359(-) (comEA) [Staphylococcus aureus strain M03/0073_III_ST239]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637614 LUZ00_RS08935 WP_001792568.1 1784673..1785359(-) (comEA) [Staphylococcus aureus strain M03/0073_III_ST239]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969