Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUZ08_RS02605 Genome accession   NZ_CP089489
Coordinates   461531..462217 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain E1174_IV_ST22     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 456531..467217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ08_RS02570 yqeH 457058..458158 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  LUZ08_RS02575 aroE 458172..458978 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  LUZ08_RS02580 yhbY 458982..459272 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  LUZ08_RS02585 nadD 459275..459844 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUZ08_RS02590 yqeK 459834..460418 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUZ08_RS02595 rsfS 460419..460772 (+) 354 WP_001088022.1 ribosome silencing factor -
  LUZ08_RS02600 - 460775..461491 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  LUZ08_RS02605 comEA 461531..462217 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  LUZ08_RS02610 - 462309..462770 (+) 462 WP_000439693.1 ComE operon protein 2 -
  LUZ08_RS02615 comEC 462775..464976 (+) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LUZ08_RS02620 holA 465033..466007 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  LUZ08_RS02625 rpsT 466052..466303 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=637380 LUZ08_RS02605 WP_001792568.1 461531..462217(+) (comEA) [Staphylococcus aureus strain E1174_IV_ST22]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637380 LUZ08_RS02605 WP_001792568.1 461531..462217(+) (comEA) [Staphylococcus aureus strain E1174_IV_ST22]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969