Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUZ05_RS02345 Genome accession   NZ_CP089481
Coordinates   436155..436841 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain E1038_IIV_ST8     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 431155..441841
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ05_RS02310 yqeH 431682..432782 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  LUZ05_RS02315 aroE 432796..433602 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  LUZ05_RS02320 yhbY 433606..433896 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  LUZ05_RS02325 nadD 433899..434468 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUZ05_RS02330 yqeK 434458..435042 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUZ05_RS02335 rsfS 435043..435396 (+) 354 WP_001088022.1 ribosome silencing factor -
  LUZ05_RS02340 - 435399..436115 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  LUZ05_RS02345 comEA 436155..436841 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  LUZ05_RS02350 - 436933..437394 (+) 462 WP_000439693.1 ComE operon protein 2 -
  LUZ05_RS02355 comEC 437399..439600 (+) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LUZ05_RS02360 holA 439657..440631 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  LUZ05_RS02365 rpsT 440676..440927 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=637203 LUZ05_RS02345 WP_001792568.1 436155..436841(+) (comEA) [Staphylococcus aureus strain E1038_IIV_ST8]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637203 LUZ05_RS02345 WP_001792568.1 436155..436841(+) (comEA) [Staphylococcus aureus strain E1038_IIV_ST8]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969