Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   LUY99_RS12785 Genome accession   NZ_CP089479
Coordinates   2523553..2524122 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 0073_III_ST239     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2518553..2529122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY99_RS12760 cysE 2519766..2520413 (+) 648 WP_001838365.1 serine O-acetyltransferase -
  LUY99_RS12765 cysS 2520397..2521797 (+) 1401 WP_000631964.1 cysteine--tRNA ligase -
  LUY99_RS12770 - 2521790..2522194 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  LUY99_RS12775 rlmB 2522202..2522948 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  LUY99_RS12780 - 2522948..2523472 (+) 525 WP_000664738.1 NYN domain-containing protein -
  LUY99_RS12785 sigH 2523553..2524122 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  LUY99_RS12790 rpmG 2524237..2524380 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  LUY99_RS12795 secE 2524436..2524618 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  LUY99_RS12800 nusG 2524631..2525179 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  LUY99_RS12805 rplK 2525360..2525782 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  LUY99_RS12810 rplA 2525990..2526682 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  LUY99_RS12815 rplJ 2526954..2527454 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  LUY99_RS12820 rplL 2527497..2527865 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  LUY99_RS12825 - 2528040..2528648 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=637187 LUY99_RS12785 WP_000872873.1 2523553..2524122(+) (sigH) [Staphylococcus aureus strain 0073_III_ST239]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=637187 LUY99_RS12785 WP_000872873.1 2523553..2524122(+) (sigH) [Staphylococcus aureus strain 0073_III_ST239]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984