Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUY99_RS02565 Genome accession   NZ_CP089479
Coordinates   543602..544288 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 0073_III_ST239     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 538602..549288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY99_RS02545 rpsT 539516..539767 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  LUY99_RS02550 holA 539812..540786 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  LUY99_RS02555 comEC 540843..543044 (-) 2202 WP_001807336.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LUY99_RS02560 - 543049..543510 (-) 462 WP_000439693.1 ComE operon protein 2 -
  LUY99_RS02565 comEA 543602..544288 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  LUY99_RS02570 - 544328..545044 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  LUY99_RS02575 rsfS 545047..545400 (-) 354 WP_001088022.1 ribosome silencing factor -
  LUY99_RS02580 yqeK 545401..545985 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUY99_RS02585 nadD 545975..546544 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUY99_RS02590 yhbY 546547..546837 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  LUY99_RS02595 aroE 546841..547647 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  LUY99_RS02600 yqeH 547661..548761 (-) 1101 WP_001280148.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=637162 LUY99_RS02565 WP_001792568.1 543602..544288(-) (comEA) [Staphylococcus aureus strain 0073_III_ST239]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637162 LUY99_RS02565 WP_001792568.1 543602..544288(-) (comEA) [Staphylococcus aureus strain 0073_III_ST239]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969