Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   LUY90_RS14250 Genome accession   NZ_CP089477
Coordinates   2852368..2853084 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 0.1345_II_ST5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2847368..2858084
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUY90_RS14230 - 2848462..2849412 (+) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -
  LUY90_RS14235 - 2849561..2851045 (+) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  LUY90_RS14240 - 2851042..2852001 (+) 960 WP_001253312.1 carbohydrate kinase -
  LUY90_RS14245 - 2852189..2852296 (-) 108 WP_001790167.1 hypothetical protein -
  LUY90_RS14250 agrA 2852368..2853084 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  LUY90_RS14255 agrC 2853103..2854395 (-) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  LUY90_RS14260 agrD 2854420..2854560 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  LUY90_RS14265 agrB 2854557..2855126 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  LUY90_RS14270 hld 2855416..2855496 (+) 81 WP_000046022.1 delta-hemolysin -
  LUY90_RS14275 - 2856093..2856878 (-) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  LUY90_RS14280 - 2857239..2857865 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=637147 LUY90_RS14250 WP_000688492.1 2852368..2853084(-) (agrA) [Staphylococcus aureus strain 0.1345_II_ST5]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=637147 LUY90_RS14250 WP_000688492.1 2852368..2853084(-) (agrA) [Staphylococcus aureus strain 0.1345_II_ST5]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1