Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   LUZ07_RS02220 Genome accession   NZ_CP089476
Coordinates   413294..413980 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 3596_II_ST8     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 408294..418980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LUZ07_RS02185 yqeH 408821..409921 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  LUZ07_RS02190 aroE 409935..410741 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  LUZ07_RS02195 yhbY 410745..411035 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  LUZ07_RS02200 nadD 411038..411607 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  LUZ07_RS02205 yqeK 411597..412181 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  LUZ07_RS02210 rsfS 412182..412535 (+) 354 WP_001088022.1 ribosome silencing factor -
  LUZ07_RS02215 - 412538..413254 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  LUZ07_RS02220 comEA 413294..413980 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  LUZ07_RS02225 - 414072..414533 (+) 462 WP_000439693.1 ComE operon protein 2 -
  LUZ07_RS02230 comEC 414538..416739 (+) 2202 WP_001807336.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LUZ07_RS02235 holA 416796..417770 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  LUZ07_RS02240 rpsT 417815..418066 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=637069 LUZ07_RS02220 WP_001792568.1 413294..413980(+) (comEA) [Staphylococcus aureus strain 3596_II_ST8]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=637069 LUZ07_RS02220 WP_001792568.1 413294..413980(+) (comEA) [Staphylococcus aureus strain 3596_II_ST8]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969