Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   N8153_RS14170 Genome accession   NZ_CP106756
Coordinates   2889984..2890640 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain B-JRPT-4119     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2884984..2895640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N8153_RS14140 (N8153_14140) yecA 2886235..2886900 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  N8153_RS14160 (N8153_14160) pgsA 2887550..2888098 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  N8153_RS14165 (N8153_14165) uvrC 2888155..2889987 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  N8153_RS14170 (N8153_14170) letA 2889984..2890640 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  N8153_RS23035 - 2890782..2890853 (+) 72 Protein_2774 transcriptional regulator -
  N8153_RS14175 (N8153_14175) yecU 2890936..2891112 (+) 177 WP_001326718.1 protein YecU -
  N8153_RS14180 (N8153_14180) yecF 2891099..2891323 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  N8153_RS14185 (N8153_14185) sdiA 2891390..2892112 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  N8153_RS14190 (N8153_14190) tcyN 2892342..2893094 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  N8153_RS14195 (N8153_14195) tcyL 2893091..2893759 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  N8153_RS14200 (N8153_14200) dcyD 2893774..2894760 (-) 987 WP_001128219.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=636423 N8153_RS14170 WP_000611335.1 2889984..2890640(-) (letA) [Escherichia coli strain B-JRPT-4119]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=636423 N8153_RS14170 WP_000611335.1 2889984..2890640(-) (letA) [Escherichia coli strain B-JRPT-4119]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486